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Understanding the Cellular Mechanisms: How Does Estrogen Lead to Osteoporosis?

According to the Endocrine Society, postmenopausal osteoporosis affects approximately 1 in 10 women over 60 worldwide. The primary driver behind this significant health issue is often estrogen deficiency, which alters the delicate balance of bone remodeling and explains **how estrogen lead to osteoporosis** by triggering a complex cascade of cellular and inflammatory events.