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Is Vymada 50 mg safe for older adults with heart failure?

While elderly patients with heart failure are often underrepresented in clinical trials, real-world data suggests that the medication sacubitril/valsartan (marketed as Vymada) is generally safe and beneficial for this population, including when starting with the Vymada 50 mg dosage. Nonetheless, close medical supervision is crucial due to a higher risk of certain side effects in older adults.