:

What is ovarian exhaustion syndrome?: Causes, Symptoms, and Management

Affecting approximately 1% of women under age 40, ovarian exhaustion syndrome, now most commonly called primary ovarian insufficiency (POI), occurs when the ovaries stop functioning normally well before the average age of menopause. This condition is marked by hormonal changes that can disrupt menstrual cycles, cause infertility, and lead to other health issues associated with low estrogen levels.