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Do you lose stem cells as you get older? The science of aging and stem cell decline

By age 70, the clonal diversity of blood-producing hematopoietic stem cells in humans is drastically reduced. It is a common misconception that humans simply "run out" of these regenerative cells; instead, the question of "Do you lose stem cells as you get older?" is more complex, revealing that both the number and function of stem cells decline with age. The body's regenerative engine becomes less efficient, a process known as stem cell exhaustion.