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What vaccines does the CDC recommend for seniors? A comprehensive guide

5 min read

With more than half of all flu-related hospitalizations occurring in adults 65 and older, it's clear that vaccination is a critical part of healthy aging. This guide addresses what vaccines does the CDC recommend for seniors to protect against serious infectious diseases and their complications.

Quick Summary

The CDC recommends several key vaccines for seniors, including annual flu and COVID-19 shots, as well as protection against shingles, pneumococcal disease, and RSV, to safeguard against severe illness.

Key Points

  • Annual Flu Shot: Adults 65+ are recommended to get a high-dose or adjuvanted flu vaccine every year.

  • Pneumonia Prevention: A new vaccine schedule for pneumococcal disease is in effect for adults 50 and older.

  • Shingles Protection: Two doses of the Shingrix vaccine are recommended for all healthy adults aged 50 and over.

  • RSV for at-risk seniors: A single dose of the RSV vaccine is recommended for all adults 75 and older, and for those 50-74 with certain risk factors.

  • Tdap Booster: Older adults should receive a Tdap booster every 10 years, especially if they haven't had one since adolescence.

  • COVID-19 Updates: Adults 65 and older are recommended to receive a second dose of the 2024-2025 COVID-19 vaccine.

In This Article

Why Vaccines Are Essential for Seniors

As we age, our immune systems naturally become weaker, a process known as immunosenescence. This change makes older adults more susceptible to serious infections and complications that might be less severe for younger individuals. Diseases like the flu, pneumonia, and shingles can lead to severe illness, hospitalization, and a decline in overall health and independence. Keeping up with immunization schedules is a proactive and effective way to bolster your body's defenses against these threats.

Annual Influenza (Flu) Vaccine

The flu can be particularly dangerous for adults aged 65 and older. Each year, the CDC recommends an updated seasonal flu vaccine to protect against the strains most likely to circulate.

Key Considerations for Seniors

  • Enhanced Options: For adults 65 and older, the CDC recommends specific enhanced flu vaccines. These versions are designed to create a stronger immune response than standard flu shots.
  • Timing: While vaccination is beneficial throughout flu season, it is often best to get vaccinated in September or October to provide strong protection through the peak season.
  • Protection: Even if the vaccine is not a perfect match for all circulating strains, it can still significantly reduce the risk of severe illness, complications, and death.

Pneumococcal Vaccines (Pneumonia)

Pneumococcal disease is a serious bacterial infection that can cause pneumonia, meningitis, and bloodstream infections. Older adults are at increased risk for severe disease. Recent CDC guidance has updated recommendations for those 50 and older.

Pneumococcal Vaccination Options (2025)

For adults 50 and older who have not previously received a pneumococcal conjugate vaccine (PCV), the CDC recommends one of the following:

  1. One dose of PCV20 or PCV21. If either of these is used, the pneumococcal vaccination is complete.
  2. If PCV15 is used, it should be followed by one dose of PPSV23 at least one year later. For immunocompromised individuals, this interval may be as short as eight weeks.

Shingles (Herpes Zoster) Vaccine

Shingles is a painful rash caused by the reactivation of the chickenpox virus and can lead to postherpetic neuralgia (PHN), a long-term nerve pain. The risk of shingles and PHN increases with age.

The Shingrix Vaccine

  • Who should get it: The CDC recommends two doses of the recombinant zoster vaccine (RZV), known as Shingrix, for healthy adults aged 50 and older. It is also recommended for immunocompromised adults aged 19 and older.
  • Dosage: The two doses are given 2 to 6 months apart.
  • Effectiveness: Shingrix is more than 90% effective at preventing shingles and PHN.

RSV (Respiratory Syncytial Virus) Vaccine

While often presenting with mild, cold-like symptoms, RSV can lead to severe lung infections, hospitalization, and death in older adults, especially those with underlying conditions.

Current RSV Recommendations

  • Ages 75 and older: The CDC recommends an RSV vaccine for all adults ages 75 and older.
  • Ages 50–74 at risk: The vaccine is also recommended for adults aged 50–74 who are at increased risk of severe RSV disease due to conditions like chronic heart or lung disease or a weakened immune system.
  • Dosage: As of the 2025-2026 season, the RSV vaccine is not an annual shot; a single dose provides protection for at least two years.

Tdap (Tetanus, Diphtheria, Pertussis) Booster

The Tdap vaccine protects against tetanus (lockjaw), diphtheria, and pertussis (whooping cough). While initial vaccination typically occurs in childhood, boosters are necessary for continued protection.

Tdap for Older Adults

  • One-time Tdap dose: Any older adult who has never received a Tdap vaccine should get one dose.
  • 10-Year Booster: Following the initial dose, a booster of either Tdap or Td (tetanus and diphtheria only) is recommended every 10 years.
  • Protection for others: The Tdap vaccine is especially important for seniors who have contact with newborns, as it helps prevent the spread of pertussis, which is very dangerous for infants.

COVID-19 Vaccine

COVID-19 remains a threat, particularly for older adults who face a higher risk of severe illness and complications. Staying up to date with the latest COVID-19 vaccine is critical.

2024–2025 Recommendations for Seniors

  • Second Dose: The CDC's Advisory Committee on Immunization Practices (ACIP) has recommended a second dose of the 2024–2025 COVID-19 vaccine for adults aged 65 and older.
  • Timing: This second dose should be given 6 months after the first 2024–2025 dose, though it can be given as early as 2 months later.
  • Vigilance: Recommendations for COVID-19 vaccines are updated regularly, so it's important to consult a healthcare provider for the most current guidance.

Comparing Key Senior Vaccines

Vaccine Target Age Group Primary Protection Typical Frequency Key Points
Influenza 65+ (all adults) Seasonal flu Annually Enhanced versions recommended for seniors.
Pneumococcal 50+ Pneumonia, meningitis Variable; can be a one-time series. New PCV recommendations for 2025.
Shingles (Shingrix) 50+ Shingles, PHN Two doses, one-time series. Highly effective, replaces older Zostavax vaccine.
RSV 75+ (or 50-74 at risk) Severe RSV infection Currently not annual; single dose. Recommended for late summer/early fall.
Tdap All adults Tetanus, diphtheria, pertussis One initial dose, booster every 10 years. Protects against whooping cough.
COVID-19 All adults COVID-19 Updated annually; extra dose for 65+. Recommendations updated frequently for variants.

Staying Up-to-Date and Proactive

Navigating the world of senior immunizations can be complex, but it's a vital part of a comprehensive healthy aging plan. Here are some actionable steps for older adults:

  • Discuss with your doctor: Talk to your healthcare provider or pharmacist about your specific health history and needs. They can create a personalized vaccination plan for you.
  • Track your records: Keep a record of the vaccines you have received, including dates, to make sure you are current on boosters and multi-dose series.
  • Plan ahead: If you are eligible for the RSV vaccine or the enhanced flu vaccine, plan to get them in late summer or early fall for maximum protection during the respiratory virus season.
  • Check coverage: Most recommended adult vaccines are fully covered by Medicare Part B or Part D with no out-of-pocket costs. Check your specific plan for details.
  • Trust authoritative sources: For detailed, up-to-date information, the CDC and other public health organizations are the most reliable sources. You can find more information on healthy aging by visiting the National Institute on Aging website Healthy Aging and Immunization.

Conclusion

Staying informed about what vaccines does the CDC recommend for seniors is one of the most effective strategies for maintaining health and vitality. Immunizations are not just for children; they are a critical tool for protecting against serious illness throughout life. By taking a proactive approach to your vaccination schedule, you can significantly reduce your risk of severe complications and enjoy a healthier, more active life as you age.

Frequently Asked Questions

Yes, as of 2023, Medicare covers all vaccines recommended by the Advisory Committee on Immunization Practices (ACIP) with no out-of-pocket costs for beneficiaries. This includes the shingles, flu, pneumococcal, RSV, and Tdap vaccines.

Yes, many vaccines, such as the flu shot and pneumococcal vaccines, can be safely administered during the same visit. You should consult your healthcare provider to discuss the best approach for you based on your vaccination history and personal needs.

For most older adults, the ideal time to get the seasonal flu vaccine is in September or October. Similarly, the CDC recommends getting the RSV vaccine in late summer or early fall, before the typical RSV season begins.

If you are an older adult and can't recall your last Tdap or Td booster, you should get a single dose of Tdap. Afterward, continue with a Td or Tdap booster every 10 years.

Yes. For adults 65 and older, the CDC preferentially recommends enhanced flu vaccines, such as high-dose or adjuvanted options, which are designed to provide a stronger immune response.

Yes, the CDC recommends that you get the shingles vaccine (Shingrix) even if you have had a past episode of shingles, as it can help prevent future occurrences.

Adults aged 50–74 are considered at increased risk for severe RSV if they have conditions like chronic heart or lung disease, a weakened immune system, or live in a nursing home. Your healthcare provider can determine if you have risk factors that warrant vaccination.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice. Always consult a qualified healthcare provider regarding personal health decisions.