Skip to content

Understanding What is the prevalence of anemia in persons 65 years and older in the United States?

5 min read

According to the CDC, anemia prevalence is highest in adults aged 60 and older. This article explores the latest national estimates and trends to answer the question, "What is the prevalence of anemia in persons 65 years and older in the United States?" and sheds light on its increasing frequency with age and significant health consequences for seniors.

Quick Summary

The Centers for Disease Control and Prevention reported that during 2021–2023, the prevalence of anemia in US adults aged 60 and older was 12.5%, the highest among all age groups.

Key Points

  • High Prevalence: Anemia affects 12.5% of US adults aged 60 and older, the highest rate among any age group, according to 2021–2023 CDC data.

  • Increases with Age: The prevalence of anemia rises steeply with advancing age. Some studies have shown rates as high as nearly 40% in men aged 85 and older.

  • Multiple Causes: Anemia in seniors is often caused by nutritional deficiencies, chronic inflammation, chronic kidney disease, or is unexplained (UAA).

  • Serious Consequences: Even mild anemia is associated with increased hospitalization, higher mortality, functional decline, and cognitive impairment in older adults.

  • Evaluation is Crucial: Diagnosis requires a systematic approach, including comprehensive blood tests and investigation for underlying causes like chronic bleeding or disease.

  • Treatment is Targeted: Management is focused on correcting the specific underlying cause, whether it's a nutritional deficiency, managing a chronic condition, or more specific interventions for unexplained anemia.

  • Disproportionate Impact: Anemia prevalence is higher in institutionalized seniors (e.g., nursing homes) and among certain racial and ethnic groups, such as Black Americans.

In This Article

Prevalence of Anemia in Older Adults: A National Overview

Anemia, a condition marked by a lower-than-normal number of red blood cells or hemoglobin, is a significant public health issue for older adults. Once dismissed as a normal part of aging, research now shows it is a key indicator of underlying health problems with serious consequences. Understanding what is the prevalence of anemia in persons 65 years and older in the United States? is crucial for effective diagnosis, treatment, and proactive senior care.

Current Prevalence Statistics from National Surveys

Based on data from the August 2021–August 2023 National Health and Nutrition Examination Survey (NHANES), the CDC found that the prevalence of anemia in US adults aged 60 and older was 12.5%. This figure is the highest across all age groups surveyed. Breaking down this statistic reveals important details about how the condition affects different populations within the senior demographic:

  • Increasing with Age: Older data from 2013–2016 illustrated a clear trend: the prevalence of anemia increases significantly with age for both men and women. For men, the prevalence rose from 7.4% at ages 65–74 to a striking 39.5% for those 85 years and older. For women, the increase was from 7.6% at ages 65–74 to 21.9% for those 85 and older.
  • Gender Differences: While overall prevalence was slightly higher in men over 65 in some studies, recent data shows different patterns. The 2021-2023 CDC brief found that while anemia prevalence for adults 60 and older was not significantly different between men and women, men aged 60+ showed a prevalence of 12.8% and women 60+ had a prevalence of 12.4%. However, significant differences appear in younger adult females and in specific racial and income groups.
  • Racial and Ethnic Disparities: The prevalence of anemia is not uniform across racial and ethnic groups. According to the same 2021-2023 CDC data, Black non-Hispanic individuals aged 2 and older had the highest prevalence (22.0%), significantly higher than White non-Hispanic individuals (6.1%), showing a pattern that persists into older age.

Common Causes of Anemia in Older Adults

Unlike in younger populations where a single cause might be responsible, anemia in seniors is often multifactorial. A comprehensive evaluation is necessary to pinpoint the underlying issues. The most common causes fall into three major categories:

  1. Nutritional Deficiencies: A significant portion of anemia in older adults can be attributed to inadequate levels of key nutrients. Iron deficiency is particularly common, often due to poor dietary intake, malabsorption, or chronic blood loss from gastrointestinal issues. Vitamin B12 and folate deficiencies are also key culprits, sometimes linked to conditions like atrophic gastritis or long-term medication use.
  2. Anemia of Chronic Inflammation/Disease: Chronic inflammatory conditions such as arthritis, infections, heart failure, and autoimmune diseases can interfere with the body's iron metabolism and erythropoietin production. Chronic kidney disease (CKD), which is more common with age, is a major contributor to anemia due to reduced erythropoietin production.
  3. Unexplained Anemia of Aging (UAA): In up to a third of cases, the cause of anemia in an elderly patient remains unexplained even after extensive evaluation. This form, UAA, is thought to be linked to age-related changes in bone marrow function, hormonal levels (like testosterone), and a low-grade inflammatory state common in older age.

The Impact of Anemia on Seniors

Anemia is not just a lab value; it has a profound and measurable impact on the health and quality of life for older adults. Even mild cases of anemia have been shown to increase the risk of poor outcomes.

  • Increased Morbidity and Mortality: Anemic seniors face higher rates of hospitalization, longer hospital stays, and increased risk of death compared to their non-anemic peers.
  • Functional and Cognitive Decline: Anemia is linked to decreased mobility, muscle strength, balance, and overall physical performance. It has also been associated with cognitive decline and a higher risk of developing dementia.
  • Higher Healthcare Costs: The increased incidence of hospitalizations, longer stays, and need for more intensive care makes anemia a significant economic burden on the healthcare system.

Comparison of Anemia Prevalence by Setting (Conceptual)

Feature Community-Dwelling Seniors Nursing Home Residents
Prevalence Estimate Approximately 12% in some studies As high as 47-56% in some studies
Severity Majority of cases are typically mild Often more severe and chronic
Contributing Factors More likely to include nutritional deficiencies, chronic disease Higher incidence of chronic disease, malnutrition, and complex health issues
Mobility Impact Associated with decreased mobility and balance Compounded by higher rates of falls and functional decline

Diagnosis and Management

The evaluation of anemia in an older person should be methodical and tailored to the individual's overall health status. The first step involves standard blood tests, including a complete blood count (CBC), to confirm anemia and determine red blood cell size. Further testing, such as measuring ferritin, B12, and folate levels, is crucial for identifying specific deficiencies.

Management focuses on treating the underlying cause:

  • Nutritional Support: Addressing deficiencies with supplements and dietary changes is a key first step. For vitamin B12 deficiency, injections may be necessary if malabsorption is an issue.
  • Treating Chronic Conditions: Managing underlying conditions like CKD, inflammatory diseases, or gastrointestinal bleeding sources is essential. For some chronic conditions, medications like erythropoiesis-stimulating agents (ESAs) may be used.
  • Addressing Unexplained Anemia: Because UAA is a diagnosis of exclusion, ongoing monitoring and management of symptoms are crucial. For some severe cases, ESA use may be considered.

For more clinical guidance on managing anemia in this population, refer to authoritative resources, such as those provided by the American Academy of Family Physicians, at the American Academy of Family Physicians website.

Conclusion

Anemia is a widespread and complex issue for the aging population in the United States, with prevalence increasing significantly with age. The latest national data indicates that over 12% of adults 60 and older are anemic, a rate that climbs dramatically in the oldest age brackets. Recognizing that anemia in seniors is a symptom of underlying pathology—rather than an inevitable consequence of aging—is critical. A systematic approach to diagnosis and a focus on treating the root cause are paramount to mitigating the serious health risks associated with anemia, including higher morbidity, mortality, and functional decline. With the aging of the US population, addressing and managing anemia effectively will become an increasingly vital component of senior healthcare.

Frequently Asked Questions

Anemia in older adults is often multifactorial, but common causes include nutritional deficiencies (especially iron, B12, and folate), anemia of chronic inflammation from conditions like arthritis or kidney disease, and unexplained anemia.

Symptoms like fatigue, weakness, and dizziness are common in anemic seniors but are often mistaken for normal signs of aging. Pallor, shortness of breath, and worsening heart conditions may also be present.

Yes, national surveys consistently show that the prevalence of anemia increases significantly with age. For example, the rate in people 85 years and older is substantially higher than in those 65-74.

Yes. Even mild anemia is associated with significant risks for older adults, including increased rates of hospitalization, falls, functional decline, and cognitive impairment.

Diagnosis typically begins with a complete blood count (CBC). Further testing, such as measuring ferritin, iron, B12, and folate levels, is then used to identify the underlying cause.

Unexplained Anemia of Aging (UAA) refers to cases where the cause of anemia remains unclear even after a thorough diagnostic workup. This accounts for up to one-third of anemia cases in seniors and may be linked to age-related changes in the bone marrow.

Yes, anemia is significantly more prevalent in institutionalized older adults, such as those in nursing homes, compared to community-dwelling seniors. This is often due to a higher burden of chronic illnesses and malnutrition in these settings.

References

  1. 1
  2. 2
  3. 3
  4. 4
  5. 5
  6. 6
  7. 7
  8. 8

Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice. Always consult a qualified healthcare provider regarding personal health decisions.