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Healthy Aging Hub

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Articles related to focusing on healthy aging, prevention, mobility, cognition, nutrition, independence, and caregiving support.

5 min

How Does Aging Affect Neurons and Neuroglia in the Brain?

While brain volume can decrease by up to 5% per decade after age 40, normal aging primarily affects brain function and cellular integrity through altered neuronal signaling and a progressive decline in neuroglial support. Understanding how does aging affect neurons and neuroglia is crucial for distinguishing between typical age-related changes and more severe neurodegenerative diseases.

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4 min

Is Gliosis Age Related? The Complex Link Between Aging and Glial Scars

Recent studies indicate that gliosis, the proliferation and hypertrophy of glial cells, is often an intensified response in aged brains compared to younger ones. While the exact mechanisms are still being explored, an age-related increase in reactive gliosis has been documented following nervous system injuries and in the context of neurodegenerative diseases. This suggests that the aging process significantly influences how glial cells behave, potentially shifting their function from supportive to more pro-inflammatory.

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