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Articles related to focusing on healthy aging, prevention, mobility, cognition, nutrition, independence, and caregiving support.

6 min

The Epigenetic Theory: What Theory of Aging Suggests That Aging Is a Result of Genes Being Switched on or off?

In a study published in 2023, Harvard Medical School researchers demonstrated for the first time that epigenetic changes can act as a primary driver of aging in mammals. This research points to the **Epigenetic Theory** as the answer to the question: **What theory of aging suggests that aging is a result of genes being switched on or off?** The theory suggests that the loss of epigenetic information over time leads to the disorganization of gene expression, ultimately causing aging.

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5 min

What is the role of SIRT6?

SIRT6-deficient mice exhibit a severe premature aging-like phenotype with a significantly shortened lifespan. This striking observation highlights the critical importance of SIRT6, a nuclear sirtuin, which plays a central role in maintaining genomic stability, regulating metabolism, and modulating aging pathways. So, **what is the role of SIRT6**?

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