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Articles related to focusing on healthy aging, prevention, mobility, cognition, nutrition, independence, and caregiving support.

6 min

What is antipsychotic polypharmacy? An overview of risks, benefits, and guidelines

With global median rates hovering around 20% in schizophrenia patients, antipsychotic polypharmacy (APP) is a common but debated practice in clinical psychiatry. In its most common form, **antipsychotic polypharmacy** refers to the concurrent use of two or more antipsychotic medications for an individual patient. While typically discouraged by treatment guidelines in favor of monotherapy, it is a strategy sometimes employed for managing difficult-to-treat symptoms.

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5 min

Is clozapine safe for elderly patients? Understanding the risks and benefits

A 2022 study highlighted the need for more research into clozapine use in older adults, who are more susceptible to medication-related side effects. While effective for treatment-resistant schizophrenia, the question remains: is clozapine safe for elderly patients, given their heightened vulnerability to adverse effects like agranulocytosis and metabolic issues?. Careful consideration and management are critical.

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