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At What Age Does Pineal Gland Calcification Occur?

Physiological calcification of the pineal gland, also known as "brain sand," is a normal and age-dependent process that can begin in the first decade of life. The incidence and extent of calcification generally increase significantly with age, with early imaging studies detecting it in children as young as 3 to 6 years old. This means that the answer to "At what age does pineal gland calcification occur?" is that it can start much earlier than many people realize, continuing to progress throughout adulthood.