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Yes, Osteoclasts Demineralize Bone Through a Unique Acid-Secreting Mechanism

Over 99% of the body's calcium is stored in the bones, a crucial mineral reservoir. So, do osteoclasts demineralize bone? The answer is a definitive yes. These specialized, multinucleated cells are the body's natural demolition crew, initiating the process of bone resorption by dissolving the mineral component of bone before degrading the organic matrix.