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Articles related to focusing on healthy aging, prevention, mobility, cognition, nutrition, independence, and caregiving support.

4 min

What is the error catastrophe theory of aging?

First proposed in 1963 by Leslie Orgel, a prominent molecular biologist, the error catastrophe theory of aging was a groundbreaking hypothesis that suggested cellular decline could result from a cascade of accumulating protein errors. Though later largely discredited as a universal mechanism for normal aging, this theory remains influential in the field of biogerontology for its insight into information transfer within cells.

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