How is excretion impacted by aging?: Changes in the kidneys, bladder, and bowel
According to the Merck Manuals, renal drug excretion decreases with aging, with clearance at age 80 often reduced to half of what it was at age 30. This significant physiological change is one of many ways that **excretion is impacted by aging**, affecting not only drug elimination but also the body's natural waste-removal processes in the kidneys, bladder, and bowel.