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Is FLAIR hyperintensity related to aging? Exploring white matter changes

By the fifth decade of life, approximately 50% of people show some degree of white matter hyperintensities (WMH) on brain imaging, and this prevalence rises significantly with age. This evidence confirms that **FLAIR hyperintensity is related to aging**, but this association is complex, influenced by vascular risk factors, genetics, and other pathologies. The appearance of these bright spots on FLAIR MRI scans is a common finding in the elderly, reflecting underlying changes in the brain's white matter.