:

Which gland degenerates in old age? Understanding the Thymus and Other Age-Related Glandular Changes

The human thymus gland, an essential organ for immune function, begins a process of degeneration called involution as early as the first year of life. This gradual shrinking and replacement by fat is a defining characteristic of aging and directly contributes to a weakening immune system later in life. Understanding **which gland degenerates in old age** provides critical insight into the science of immunosenescence.