Does CSF increase with age? Separating Normal Aging from Pathology
According to a study published in 2023, the intracranial cerebrospinal fluid (CSF) volume in healthy individuals was estimated to increase by approximately 30 mL (about 2%) per decade from age 20 to 80. This suggests that yes, CSF does increase with age, but the underlying mechanisms and implications for healthy aging are complex and widely misunderstood.