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Articles related to focusing on healthy aging, prevention, mobility, cognition, nutrition, independence, and caregiving support.

4 min

How does age affect the function of T cells?

By age 65, the annual influenza vaccine's effectiveness can drop from 70–90% to as low as 30–40% in younger adults, underscoring a significant decline in immune function. This phenomenon illustrates how age affects the function of T cells, key players in our adaptive immune system, leading to a diminished response to new pathogens and vaccinations. This age-related decline, known as immunosenescence, affects multiple cellular and metabolic processes, fundamentally altering how T cells operate.

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4 min

How Does Inflammation Contribute to Frailty?

According to research published in *BMC Geriatrics*, elevated inflammation is a notable characteristic in older adults, correlating with the progression of frailty. The process by which inflammation contributes to frailty is complex, involving multiple physiological systems and the dysregulation of the body's immune response over time. Chronic, low-grade inflammation, often termed 'inflammaging,' creates a pro-inflammatory state that accelerates cellular aging and functional decline.

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