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The Impact of NLRP3 Depletion on Aging-Related Metaflammation, Cognitive Function, and Social Behavior in Mice

Research indicates that aging is a major risk factor for chronic diseases associated with low-grade, systemic inflammation. This process, termed 'inflammaging,' is significantly influenced by the NLRP3 inflammasome, making the study of what is the impact of NLRP3 depletion on aging related metaflammation cognitive function and social behavior in mice a critical area of investigation.