Articles related to focusing on healthy aging, prevention, mobility, cognition, nutrition, independence, and caregiving support.
A 2019 study published in *Geroscience* revealed that topical rapamycin reduced markers of cellular senescence and aging in human skin. This compelling finding has fueled the popular question: does rapamycin make you look younger?
In many animal models, studies have shown that down-regulation of the growth hormone (GH)/IGF-1/insulin pathway can significantly prolong lifespan. However, the question of **does IGF-1 slow aging** is highly controversial in human research, with conflicting evidence suggesting both potential benefits and risks. The answer is not a simple yes or no, but rather a complex interplay influenced by genetics, age, and lifestyle.
In animal studies, reducing insulin signaling has been repeatedly linked to an increase in lifespan. While the hormone itself is not directly a culprit, elevated insulin levels and insulin resistance—a condition known as hyperinsulinemia—are strongly implicated in promoting age-related cellular damage, accelerating the aging process.
Despite some anecdotal claims of short-term benefits, a systematic review published in March 2025 concluded that while meat is suitable for muscle growth, the carnivore diet is a poor choice for healthy aging and longevity due to long-term side effects. The carnivore diet is not scientifically supported as a method to effectively slow the aging process.
According to a 2014 study in *Cell Metabolism*, a high-protein diet in middle age can significantly increase the risk of overall and cancer-related mortality. The question, **does animal protein age you faster**, is gaining traction as researchers continue to explore the intricate connection between diet and the biological processes of aging.
Recent studies have shown that a reduced protein intake can play a critical role in longevity and metabolic health in model organisms like rodents. The question, "Does protein restriction increase longevity?", however, has a much more nuanced answer in humans, with the effects varying significantly based on age and health status.
According to a study published in the American Journal of Clinical Nutrition, dietary protein intake in midlife, especially from plant sources, is associated with higher odds of healthy aging. The question of whether a high protein diet slows aging is complex, as research indicates that while higher protein benefits older adults, excessive intake in middle age may have negative effects.
The current maximum human lifespan is estimated to be around 120 years, a limit not determined by lifestyle alone but by fundamental biological and genetic mechanisms. Understanding why can't humans live longer requires delving into the intricate processes that govern cellular health and genetic stability throughout our lives.
