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Articles related to focusing on healthy aging, prevention, mobility, cognition, nutrition, independence, and caregiving support.

Oct 20, 2025

4 min

The Impact of NLRP3 Depletion on Aging-Related Metaflammation, Cognitive Function, and Social Behavior in Mice

Research indicates that aging is a major risk factor for chronic diseases associated with low-grade, systemic inflammation. This process, termed 'inflammaging,' is significantly influenced by the NLRP3 inflammasome, making the study of what is the impact of NLRP3 depletion on aging related metaflammation cognitive function and social behavior in mice a critical area of investigation.

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Oct 19, 2025

4 min

How Does the Inflammasome Affect Aging?

Chronic, low-grade inflammation, dubbed “inflammaging,” is a hallmark of the aging process and is significantly driven by inflammasomes. This critical component of the innate immune system, which normally protects against pathogens, can become overactive with age, profoundly affecting how the body breaks down and leading to an increased risk of age-related diseases.

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