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What organs are affected by brittle bone disease? A Comprehensive Guide

Affecting approximately 1 in 15,000 to 20,000 births, Osteogenesis Imperfecta (OI), or brittle bone disease, is a genetic disorder of connective tissue that extends far beyond the skeletal system. While its primary hallmark is fragile bones, it is a systemic condition, meaning it can cause complications in numerous other organs and bodily systems due to the body's inability to produce sufficient or high-quality collagen.