Skip to content
Healthy Aging Hub

:

Articles related to focusing on healthy aging, prevention, mobility, cognition, nutrition, independence, and caregiving support.

5 min

The Dual Role of CDKN2A: Unpacking Its Complex Role in Aging

The expression of the CDKN2A gene is a potent biomarker of biological age, with its protein levels increasing exponentially in human tissues over a lifespan. This critical gene plays a complex role in aging by both suppressing tumors and contributing to age-related decline through the regulation of cellular senescence.

Read Healthy Aging
5 min

What are the markers of senescent macrophages?

Cellular senescence, a hallmark of aging, affects various cell types, including immune cells like macrophages. An accumulation of these non-proliferating but metabolically active senescent macrophages contributes significantly to age-related decline and chronic inflammation. But what are the specific markers that define this cellular state?

Read Healthy Aging