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Articles related to focusing on healthy aging, prevention, mobility, cognition, nutrition, independence, and caregiving support.

Oct 18, 2025

3 min

Is Plasminogen Activator Inhibitor 1 (PAI-1) a Marker and a Mediator of Senescence?

Studies show a significant increase in circulating plasminogen activator inhibitor 1 (PAI-1) levels with both chronological and accelerated aging. This has led researchers to investigate whether PAI-1 is merely an indicator or if it actively influences the process of cellular senescence.

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