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Articles related to focusing on healthy aging, prevention, mobility, cognition, nutrition, independence, and caregiving support.

5 min

A Real-World Look: Are SGLT2 inhibitors safe in very elderly diabetic type 2 patients in real life?

Real-world studies indicate that SGLT2 inhibitors are generally safe and well-tolerated in very elderly diabetic type 2 patients, though special attention to potential side effects like volume depletion is warranted for fragile individuals. Addressing the safety of SGLT2 inhibitors for this population requires careful consideration of both the significant cardiorenal benefits and specific risks.

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4 min

Which Pharmacokinetic Changes Would Be Expected in an Elderly Client? A Guide to Senior Medication Management

As the population ages, understanding the physiological shifts that impact medication effectiveness is more important than ever. The aging process significantly alters how the body processes drugs, and knowing **which pharmacokinetic changes would be expected in an elderly client** is crucial for preventing adverse drug reactions and ensuring proper treatment. These changes involve the entire journey of a drug through the body, from the moment it is taken until it is fully eliminated.

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5 min

Why are older adults frequently needing careful titration of their drug doses?

As people age, a number of physiological changes occur, influencing how medications are handled by the body. These natural shifts mean that older adults are not simply smaller versions of younger adults when it comes to medication, which is why older adults are frequently needing careful titration of their drug doses.

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4 min

How does volume of distribution change with age?

The volume of distribution (Vd) is a crucial pharmacokinetic parameter that indicates how a drug distributes between the plasma and other tissues in the body. As individuals age, significant shifts in body composition and organ function occur, causing Vd to change dramatically and necessitating dosage adjustments to ensure safety and effectiveness.

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4 min

What is the screening tool for older people's prescriptions? An Expert Guide

According to the National Institutes of Health, over 36% of older adults take five or more medications, a practice known as polypharmacy, which significantly increases the risk of adverse drug events. Effective screening is crucial, and the primary tools used for older people's prescriptions include the Beers Criteria and the STOPP/START criteria.

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5 min

Can barbiturates cause dementia? Understanding the long-term cognitive risks

Studies have shown that long-term use of certain central nervous system depressants can lead to significant cognitive impairment in older adults. This raises a critical concern: can barbiturates cause dementia, or do they simply mimic the symptoms? We explore the documented risks associated with these powerful sedatives.

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5 min

Why seniors have an increased risk with medications?

Over 85% of older adults take at least one prescription medication, yet age-related physiological changes mean standard dosages can pose increased risks for seniors. Understanding these risks is vital for ensuring medication safety in later life and explaining **why seniors have an increased risk with medications**.

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4 min

Understanding What Drug Could Slow Down Aging: A Look at Promising Research

According to the World Health Organization, the number of people aged 65 or over is projected to triple by 2050, accelerating the search for interventions to extend healthy lifespan. In this context, the question of what drug could slow down aging has become a central focus of modern scientific inquiry, with several existing and experimental compounds showing potential in animal studies and early human trials.

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5 min

What is the best anti-aging drug? A comprehensive guide

According to the World Health Organization, the global population of people aged 60 years and over will increase from 1 billion in 2020 to 1.4 billion by 2030, driving significant interest in the science of life extension. In this context, the question arises: **What is the best anti-aging drug?** The reality is that no single 'best' drug exists; instead, researchers are exploring several compounds with potential to extend healthspan and slow the aging process.

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6 min

Why do older adults have more problems with medications than younger people do?

According to the FDA, normal body changes caused by aging can increase the chance of unwanted or harmful drug interactions, which is a key reason why older adults have more problems with medications than younger people do. A combination of physiological shifts and complex medication regimens contributes to this heightened risk, demanding careful management and awareness.

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