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What is the drug of choice for depression in the elderly?

According to the American Psychiatric Association, selective serotonin reuptake inhibitors (SSRIs) are suggested as a first-line treatment for major depressive disorder in older adults. Selecting the ideal medication, however, depends on balancing effectiveness with potential side effects and drug interactions in this population. Finding the optimal drug of choice for depression in the elderly requires careful consideration and a 'start low, go slow' approach.