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The Paradox of Decreased Parathyroid Hormone Level: How It Can Increase Bone Mineral Density While Increasing Fracture Risk

Contrary to the assumption that low parathyroid hormone (PTH) levels cause osteoporosis, research shows that a decrease in PTH, a condition known as hypoparathyroidism, typically results in paradoxically higher bone mineral density (BMD). However, this denser bone is often brittle and can increase the risk of certain fractures due to poor bone quality. This article clarifies how a decreased parathyroid hormone level impacts bone health in unexpected ways.