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Articles related to focusing on healthy aging, prevention, mobility, cognition, nutrition, independence, and caregiving support.

Oct 21, 2025

5 min

What are the markers of senescent macrophages?

Cellular senescence, a hallmark of aging, affects various cell types, including immune cells like macrophages. An accumulation of these non-proliferating but metabolically active senescent macrophages contributes significantly to age-related decline and chronic inflammation. But what are the specific markers that define this cellular state?

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Oct 21, 2025

3 min

Is Senescence-Associated β-galactosidase (SA-β-gal) a Marker of Neuronal Senescence?

Over the last two decades, the field of aging has seen extensive research into cellular senescence, a process marked by irreversible growth arrest. Yet, in post-mitotic cells like neurons, the reliability of common biomarkers such as senescence-associated β-galactosidase (SA-β-gal) remains a subject of intense debate.

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