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Articles related to focusing on healthy aging, prevention, mobility, cognition, nutrition, independence, and caregiving support.

4 min

What happens to cells when they get old? A deep dive into cellular senescence

According to the National Institute on Aging, biological aging occurs at the cellular level and can be influenced by lifelong environmental factors, heredity, and lifestyle. Understanding **what happens to cells when they get old** is key to grasping the fundamental processes that contribute to overall physical decline and age-related diseases.

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5 min

What are the characteristics of cellular senescence and its impact on aging?

First described in the 1960s, cellular senescence was identified as a stable and permanent state of cell cycle arrest. Understanding **what are the characteristics of cellular senescence** is crucial for unlocking the mysteries of aging and age-related diseases. Senescence is a double-edged sword, serving vital protective functions early in life, but contributing to a range of chronic pathologies when it persists.

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4 min

What are the hallmarks of cell senescence?

Cellular senescence, a state of irreversible cell cycle arrest, is a fundamental driver of aging and age-related disease. Defined by distinct characteristics, understanding what are the hallmarks of cell senescence provides critical insights into the biological processes behind aging and offers potential pathways for therapeutic intervention.

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4 min

What is the Process of Senescence and Why Does It Happen?

Cellular senescence is believed to be a double-edged sword, acting both as a protective barrier to cancer in youth and a driver of age-related disease later in life. As research continues to unravel its complexities, understanding **what is the process of senescence** becomes crucial for comprehending the very nature of aging itself.

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4 min

What are the features of cellular senescence?

Cellular senescence is a stable, irreversible cell cycle arrest that prevents the proliferation of damaged cells and becomes more prevalent with age. Understanding what are the features of cellular senescence provides deep insights into the mechanisms of aging and age-related diseases.

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4 min

Understanding Which Factor Contributes to Immune Senescence as People Age?

Studies show that by age 50, T-cell production can be less than 10% of its peak, illustrating the significant impact of aging on our immunity. A key medical concern is understanding **which factor contributes to immune senescence as people age**, leading to a weaker defense against infections and diseases.

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4 min

How do fibroblasts contribute to aging? Investigating the mechanisms of cellular senescence

Over 50% of the dry weight of skin is collagen, a protein primarily produced by fibroblasts that declines significantly with age. Understanding **how do fibroblasts contribute to aging** is key to unlocking the secrets behind age-related tissue decline, chronic inflammation, and diseases across the body, not just in the skin. This authoritative guide delves into the molecular and cellular mechanisms of fibroblast aging.

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