Are osteocytes affected by postmenopausal osteoporosis?: Unpacking the cellular drivers of bone loss
In postmenopausal women, a rapid decline in estrogen leads to an increase in bone fragility. Mounting scientific evidence confirms that a primary driver of this pathology is that yes, **osteocytes are affected by postmenopausal osteoporosis**, playing a critical, active role in its development through a variety of cellular pathways. The once-held belief that osteocytes were passive, embedded cells has been replaced by an understanding that their dysfunction directly contributes to bone loss.