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Articles related to focusing on healthy aging, prevention, mobility, cognition, nutrition, independence, and caregiving support.

5 min

What are the triggers of senescence? A Deep Dive into Cellular Aging

Cellular senescence, a state of irreversible cell cycle arrest, is a powerful anti-cancer mechanism, yet it paradoxically drives the aging process. The question of what are the triggers of senescence is central to understanding both disease prevention and age-related decline, involving complex cellular responses to various forms of damage.

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4 min

What are the markers for senescence in the brain?

While brain aging trajectories are incredibly variable across individuals, research shows that the accumulation of senescent cells is a significant hallmark of both aging and neurodegenerative diseases. These cells, which have undergone an irreversible cell cycle arrest, are identified by a multi-marker approach, as no single marker can definitively prove senescence in the brain.

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4 min

What are senotherapeutics for healthy aging? A comprehensive guide

Cellular senescence, a state where cells stop dividing but remain metabolically active, is a major hallmark of aging. Recent advances in geroscience have led to the development of **senotherapeutics for healthy aging**, a class of compounds designed to target these dysfunctional cells and mitigate their harmful effects on the body.

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