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Articles related to focusing on healthy aging, prevention, mobility, cognition, nutrition, independence, and caregiving support.

4 min

Is sirt2 a therapeutic target for age related disorders?

The human sirtuin family of proteins, responsible for regulating crucial cellular processes, includes Sirtuin 2 (SIRT2), a deacetylase that is most abundant in the brain and increases with age. This has fueled intense research into whether and how SIRT2 could be a therapeutic target for age-related disorders like Alzheimer's disease (AD) and Parkinson's disease (PD).

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5 min

What is the role of SIRT6?

SIRT6-deficient mice exhibit a severe premature aging-like phenotype with a significantly shortened lifespan. This striking observation highlights the critical importance of SIRT6, a nuclear sirtuin, which plays a central role in maintaining genomic stability, regulating metabolism, and modulating aging pathways. So, **what is the role of SIRT6**?

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4 min

What is a SIRT6 Activator for Longevity and Healthy Aging?

According to extensive research on sirtuin proteins, activation of Sirtuin 6 (SIRT6) has shown significant potential for extending healthspan and lifespan in animal models. A SIRT6 activator for longevity is a compound designed to increase the activity of the SIRT6 enzyme, which plays a crucial role in maintaining genomic stability and regulating metabolism to support healthy aging.

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