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What is the most common age-related change to the nervous system?

According to research from MedlinePlus, normal aging is associated with a slowing of thought and reaction time. This is the most consistently found and universal change associated with the nervous system, affecting how signals travel and how the brain processes information. It's a key aspect of aging that influences everything from physical reflexes to cognitive function. So, what is the most common age-related change to the nervous system and how does it manifest?