:

The Crucial Role of Dendrites in Aging: From Pruning to Plasticity

Dendrites, the branching projections of neurons, undergo significant morphological and functional changes during the aging process. A key finding is that neurons experience a reduction in the complexity of their dendritic arborization and a decrease in dendritic length with advancing age, contributing to observable declines in cognitive function. Understanding these transformations is critical for revealing the underlying mechanisms of age-related cognitive impairment and developing interventions to promote healthy brain aging.