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What is the degeneration of the thymus?

The thymus, a vital organ for immune system function, begins a process of degeneration and shrinking called involution shortly after birth in humans. This natural phenomenon, accelerated after puberty, causes the gland's functional tissue to be replaced with fat over time. This age-related atrophy has profound implications for T-cell production, making the process of what is the degeneration of the thymus a key factor in immunosenescence and overall health.