Which state has the highest rate of Alzheimer's?

Oct 11, 2025 3 min read •

senior care Healthy Aging dementia

According to a 2023 study published in Alzheimer's & Dementia, the highest prevalence of Alzheimer's dementia is in the east and southeastern United States, with Maryland leading the list with a prevalence of 12.9%. While Maryland has the highest rate, other states in the same region, and factors beyond geography, contribute to these statistics. This article explores the nuances behind the data to answer which state has the highest rate of Alzheimer's.

Quick Summary

Maryland is reported to have the highest prevalence of Alzheimer's dementia among the states, with other states in the east and southeast following closely, driven by demographic factors like age, racial diversity, and health inequities.

Key Points

Maryland has the highest prevalence rate: A 2023 study found Maryland to have the highest rate of Alzheimer's dementia among adults 65+, at 12.9%.
Prevalence vs. total cases: While Maryland has the highest rate, states with larger overall populations, like California and Florida, have a higher total number of people with Alzheimer's.
Higher rates in the East and Southeast: The eastern and southeastern regions of the U.S. show a consistently higher prevalence of Alzheimer's dementia overall.
Key demographic factors: Age, race, ethnicity, and socioeconomic status significantly impact prevalence, with higher rates observed in older, Black, and Hispanic populations.
Modifiable risk factors: Lifestyle choices such as physical activity, diet, and management of chronic conditions (hypertension, diabetes) can help reduce risk.
Varying diagnosis rates: Diagnosis rates and treatment access for dementia differ across the country, which can affect state-level statistics.
Importance of localized data: State- and county-specific data are vital for public health officials to target resources effectively and develop relevant strategies.

Understanding Alzheimer's Prevalence

Prevalence refers to the proportion of a population with Alzheimer's dementia at a specific time, distinct from the total number of people affected. Research examines both the absolute number of cases and the rate per capita.

States with the Highest Prevalence

Recent studies show the highest Alzheimer's prevalence rates in the eastern and southeastern U.S.. The states with the highest prevalence estimates for adults 65 and older are:

Maryland: 12.9%
New York: 12.7%
Mississippi: 12.5%
Florida: 12.5%
Louisiana: 12.4%
New Jersey: 12.3%

States with larger populations, such as California, Florida, and Texas, have the highest total number of individuals with Alzheimer's due to more older residents.

Demographic and Socioeconomic Factors

Age is the primary risk factor for Alzheimer's. However, other factors also significantly influence prevalence rates.

Racial and Ethnic Disparities: Older Black Americans have about twice the risk, and older Hispanic Americans about one and a half times the risk, of Alzheimer's or other dementias compared to older White Americans. States with larger proportions of these groups tend to have higher prevalence.
Social Determinants of Health: Factors like lower education and limited healthcare access are associated with higher dementia rates. Chronic conditions such as hypertension and diabetes also increase risk.
Geographic Variations in Diagnosis: The likelihood of a timely dementia diagnosis varies geographically, contributing to differences in prevalence data and highlighting healthcare access issues.

Comparison of States with High Alzheimer's Prevalence

The distribution of Alzheimer's is influenced by demographics, particularly in the southeastern U.S..


State	Estimated Prevalence (65+)	Contributing Factors	Initiatives and Resources
Maryland	12.9%	Higher proportions of older adults and African Americans.	Focus on awareness and support.
New York	12.7%	Large elderly and diverse urban populations.	Statewide plans to improve care.
Mississippi	12.5%	High percentages of African Americans and related health inequities.	Public health strategies for high-risk groups.
Florida	12.5%	Large older adult population.	Significant resources for senior care.

Proactive Strategies for Prevention and Support

While age and genetics are unchangeable risk factors, lifestyle and healthcare access can affect Alzheimer's risk.

Prioritize Brain Health: Engage in mentally stimulating and social activities.
Maintain Physical Activity: Regular exercise improves brain function.
Adopt a Healthy Diet: The MIND diet, rich in fruits, vegetables, and whole grains, may reduce risk.
Manage Chronic Conditions: Controlling hypertension, diabetes, and cholesterol can lower dementia risk.
Address Hearing and Vision Loss: Addressing hearing loss, for instance with aids, can mitigate associated dementia risk.

The Importance of State-Specific Data

Accurate, local data is vital for effective public health planning and resource allocation in communities with the greatest need. Understanding how demographics and risk factors interact locally helps develop targeted interventions.

The increasing number of individuals affected by dementia underscores the need for ongoing research and public health efforts. Focusing on modifiable risks and healthcare equity can support aging populations and potentially reduce future prevalence.

Visit the Alzheimer's Association website for extensive information on the disease.

Conclusion

Although Maryland has the highest prevalence rate, Alzheimer's risk and impact involve complex factors. Regional trends, demographic disparities, and socioeconomic conditions contribute to varying prevalence across states. Addressing these requires a multifaceted approach, focusing on individual health and systemic improvements in healthcare and equity.

Frequently Asked Questions

Yes, according to a 2023 study published in Alzheimer's & Dementia, Maryland was found to have the highest estimated prevalence of Alzheimer's dementia for adults aged 65 and older, at 12.9%. However, several other southeastern states have rates very close to Maryland's.

The higher rates in these regions are likely due to a combination of factors. This includes a higher proportion of older residents and significant demographic disparities, with higher concentrations of Black and Hispanic individuals, who face a greater risk for the disease.

Yes. While larger states may not have the highest prevalence rate, they often have the highest total number of people living with Alzheimer's simply because of their larger overall populations. For example, California, Florida, and Texas have the highest number of people with Alzheimer's.

Prevalence is the proportion or percentage of a population with a condition, like Alzheimer's. Total cases is the absolute number of people with the condition. A smaller state can have a higher prevalence rate than a larger state, even if the larger state has a greater total number of people affected.

While some risk factors like age and genetics are non-modifiable, you can take steps to promote brain health and potentially lower your risk. These include staying physically and mentally active, eating a healthy diet, managing chronic conditions, and staying socially engaged.

Disparities in healthcare, including differences in access to care and diagnosis intensity, can affect state-level statistics. Studies show that diagnosis rates can vary by location and demographic group, which could impact the accuracy of prevalence data and timely interventions.

State-specific data on Alzheimer's prevalence can help public health officials and policymakers identify areas with the greatest need. This information allows for the better allocation of resources, development of targeted support programs, and creation of region-specific strategies for Alzheimer's care.

References

Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice. Always consult a qualified healthcare provider regarding personal health decisions.