Universal targets with individualized care
While there was past discussion about ideal blood pressure (BP) goals for older adults, the 2025 American Heart Association (AHA) and American College of Cardiology (ACC) guidelines recommend a unified goal of less than 130/80 mmHg for most adults, including those aged 65 and older. This aligns with evidence suggesting benefits across age groups from tighter BP control.
However, this target should be individualized for seniors with significant comorbidities, frailty, or limited life expectancy. Treatment decisions should involve discussions between the patient and healthcare team to weigh benefits against risks. This moves away from a strict age-based number towards an approach based on a patient's overall health.
The new PREVENT risk calculator
A key change in the 2025 guidelines is the introduction of the PREVENT™ (Predicting Risk of cardiovascular disease EVENTs) risk calculator. This tool provides a more comprehensive risk assessment to guide treatment, particularly for those with Stage 1 hypertension (BP of 130–139/80–89 mmHg).
PREVENT incorporates various factors, such as:
- Demographics: Age, sex, race.
- Lifestyle: Smoking status.
- Biometrics: Systolic and diastolic BP, cholesterol levels, and BMI.
- Medical History: Diabetes and medication use.
- Social Determinants: ZIP code.
- Biomarkers: Kidney function, blood glucose, and urine albumin-to-creatinine ratio.
For seniors, PREVENT helps determine the timing and intensity of treatment. Those with Stage 1 hypertension and a high predicted 10-year CVD risk ($\geq 7.5\%$) are advised to start medication along with lifestyle changes. Individuals at lower risk may try lifestyle changes for 3 to 6 months before considering medication.
Emphasis on early intervention
The new guidelines strongly emphasize early intervention for both heart and brain health, highlighting the link between high BP and increased risk of cognitive decline and dementia. The guideline recommends aiming for a systolic BP below 130 mmHg to prevent cognitive impairment and dementia. This is particularly relevant for seniors and underscores the importance of proactive BP management for long-term brain function.
Comparison of 2017 vs. 2025 guidelines for seniors
Feature | 2017 AHA/ACC Guideline | 2025 AHA/ACC Guideline |
---|---|---|
Recommended BP Target for Seniors | Generally <130/80 mmHg for community-dwelling seniors 65+. |
Universal goal of <130/80 mmHg for most adults, including seniors, if tolerated. |
Risk Assessment Tool | Pooled Cohort Equations (PCE) based on 10-year ASCVD risk. | PREVENT™ calculator, more comprehensive, assesses 10-year and 30-year total CVD risk. |
Stage 1 Hypertension (130-139/80-89 mmHg) - Low Risk | Lifestyle intervention, re-evaluate in 3-6 months. | Lifestyle intervention, re-evaluate in 3-6 months; if still high, initiate medication. |
Stage 1 Hypertension (130-139/80-89 mmHg) - High Risk | Medication recommended. | Medication recommended immediately, based on PREVENT risk score ($\geq 7.5\%$). |
Stage 2 Hypertension ($\geq 140/90$ mmHg) | Initiate medication. | Initiate combination therapy with two agents, preferably as a single-pill combination. |
Cognitive Decline Prevention | BP lowering is reasonable to prevent. | Stronger recommendation: Goal of <130 mmHg systolic BP is recommended to prevent. |
Emphasis on Frailty | Clinical judgment, patient preference are reasonable. | Individualization of care emphasized in substantial frailty. |
Lifestyle modifications and multidisciplinary care
The updated guidelines reinforce the importance of lifestyle modifications for all adults, including seniors. These include:
- Dietary Adjustments: Following a heart-healthy diet like DASH, focusing on low sodium (ideally 1500 mg/day) and rich in fruits, vegetables, and whole grains.
- Physical Activity: Engaging in regular moderate activity, including aerobic exercise (75–150 minutes per week) and resistance training.
- Stress Management: Using techniques such as meditation and yoga.
- Home Monitoring: Using a validated at-home monitor for better accuracy and tracking.
- Team-Based Care: Encouraging a multidisciplinary team approach involving various healthcare professionals to support patients.
Conclusion
The 2025 AHA/ACC guidelines advocate for a universal BP target of <130/80 mmHg
for most adults, including seniors, while emphasizing individualized care based on overall health and frailty. The new PREVENT risk calculator offers a more precise method for assessing risk and tailoring treatment. A significant point for seniors is the strengthened evidence linking earlier and more intensive BP control to a reduced risk of cognitive decline and dementia. The guidelines promote a comprehensive approach combining lifestyle changes, early medication for those at risk, team-based care, and home monitoring. Seniors should consult their healthcare provider for personalized recommendations.
This article is for informational purposes only and does not constitute medical advice. Consult a healthcare professional for diagnosis and treatment.