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What are the side effects of the RSV vaccine for seniors?

3 min read

According to the CDC, older adults face a significantly higher risk of severe illness from respiratory syncytial virus (RSV), with the potential for serious complications. Knowing what to expect regarding the side effects of the RSV vaccine for seniors is crucial for making informed health decisions and ensuring peace of mind during vaccination season.

Quick Summary

The RSV vaccine typically causes mild, temporary side effects in seniors, such as soreness at the injection site, fatigue, and headache, which usually resolve within a few days. While rare, serious adverse events like Guillain-Barré syndrome have been reported and require prompt medical attention.

Key Points

  • Common Side Effects are Mild: Seniors typically experience mild and temporary side effects, such as pain at the injection site, fatigue, and headache.

  • Duration of Symptoms is Short: Most common side effects, including muscle aches and fever, resolve within 48 hours.

  • Rare Side Effects are Possible: Serious but very rare neurological events, including Guillain-Barré Syndrome (GBS), have been reported in clinical trials.

  • Vaccine Varies by Brand: Different FDA-approved vaccines, such as Arexvy and Abrysvo, may have slightly different side effect profiles and compositions.

  • Benefits Outweigh the Risks: The potential for mild, temporary side effects is far less than the risk of severe illness or death from an RSV infection in vulnerable older adults.

  • Manage Symptoms at Home: For mild symptoms like soreness or fever, home care such as rest, hydration, and cool compresses can provide relief.

  • Know When to Seek Medical Help: Signs of a serious allergic reaction or neurological symptoms like tingling or weakness require immediate medical attention.

In This Article

Common Side Effects in Seniors

Like most vaccinations, the RSV shot can cause side effects as the immune system learns to recognize and fight the virus. For older adults, these reactions are typically mild and temporary, similar to those experienced with a flu shot or COVID-19 vaccine.

Injection Site Reactions

These are the most common side effects and occur at the spot on the arm where the vaccine was administered. They usually appear within a day or two and include:

  • Pain or soreness: The most frequently reported symptom.
  • Redness: Mild discoloration around the injection site.
  • Swelling: A slight puffiness that subsides quickly.

Systemic Symptoms

Some seniors may experience more general, flu-like symptoms as their body builds immunity. These can include:

  • Fatigue or tiredness: A general feeling of being unwell and low on energy.
  • Headache: Mild to moderate head pain.
  • Muscle or joint pain: Aches in the body, particularly around the vaccinated arm.
  • Nausea: A feeling of sickness in the stomach.
  • Fever: A low-grade temperature is possible but less common.
  • Diarrhea: This has been reported in clinical trials, though sometimes at similar rates in placebo groups depending on the vaccine.

Comparing Arexvy and Abrysvo Side Effects

As of recent approvals, older adults have several RSV vaccine options, primarily Arexvy (GSK) and Abrysvo (Pfizer). While they share many common side effects, there are subtle differences in their formulations that may affect an individual's experience.

Feature Arexvy (GSK) Abrysvo (Pfizer)
Type Recombinant protein subunit, contains an adjuvant to boost immune response. Recombinant protein subunit, bivalent (contains proteins for RSV A and B), does not contain an adjuvant.
Common Side Effects Injection site pain, fatigue, headache, muscle pain. Injection site pain, fatigue, headache, muscle pain. Also may cause nausea and diarrhea.
Rare Concerns Neurologic conditions like GBS (rare), brain and spinal cord inflammation (very rare, especially when given with other vaccines). Neurologic conditions like GBS (rare), atrial fibrillation (rare irregular heart rhythm).

How Long Do Side Effects Last?

For most older adults, common side effects are short-lived. Aches, headaches, and fatigue generally improve within 24 to 48 hours. Injection site soreness might linger for a few days but is usually mild and doesn't interfere with daily activities. Some seniors may not experience any side effects at all.

Managing Mild Symptoms at Home

For the majority of people, managing post-vaccination symptoms is straightforward and can be done with simple at-home care:

  • For injection site discomfort: Applying a clean, cool compress to the area can help reduce pain and swelling. Gentle arm movement can also reduce stiffness.
  • For fever or headache: Over-the-counter pain relievers like acetaminophen can provide relief. Always consult a pharmacist or doctor before taking new medication.
  • For fatigue: Plan to rest and take it easy for a day or two after your vaccine. Keep your schedule light to allow your body to recover.
  • For nausea or diarrhea: Stay hydrated with plenty of fluids. Consider eating smaller, more frequent meals and avoiding spicy or greasy foods.

When to Contact a Healthcare Provider

While severe reactions are very rare, it is important to know the warning signs. You should contact your healthcare provider immediately if you experience:

  • Symptoms of Guillain-Barré Syndrome (GBS): This includes sudden weakness or tingling in the hands or feet, difficulty walking, or sharp pain.
  • Signs of an allergic reaction: Hives, swelling of the face, tongue, or throat, or difficulty breathing warrant immediate medical attention.
  • Worsening or prolonged symptoms: If your mild symptoms last longer than a few days, become more severe, or are a cause for concern.

The Bottom Line for Seniors

Getting vaccinated against RSV is a crucial step in protecting older adults from potentially life-threatening complications, which include severe pneumonia and worsening of existing conditions like COPD or asthma. The common side effects are generally mild and temporary, and the risk of serious complications from the vaccine is far outweighed by the benefits of protection against the virus. Discussing the vaccine with your healthcare provider will help determine the best course of action based on your individual health needs. For the most up-to-date information on RSV vaccination, consult the official CDC website.

Frequently Asked Questions

No, side effects can vary. While most seniors experience similar mild reactions, individual health status and which vaccine brand is received can influence the specific side effects experienced.

Common side effects like pain, fatigue, and headache are usually short-lived, resolving within a few days. Many seniors report feeling back to normal within 24 to 48 hours.

Both vaccines share many common side effects. However, clinical trials noted that Abrysvo may also cause nausea and diarrhea, while Arexvy is less associated with these specific symptoms.

A very small number of GBS cases were reported in clinical trials for Arexvy and Abrysvo, and an increased risk is supported by post-licensure data. The risk is considered very low, but healthcare providers continue to monitor for any neurologic conditions following vaccination.

For mild symptoms, rest, stay hydrated, and use over-the-counter pain relievers if appropriate. Apply a cool compress to the injection site for soreness. If symptoms are severe, worsen, or don't go away, contact a healthcare provider.

Yes, the RSV vaccine can be given at the same time as other vaccines, including the flu and COVID-19 shots. However, some people may experience an increase in side effects when receiving multiple vaccines at once.

Seek emergency medical help if you experience signs of a severe allergic reaction, such as hives, swelling of the face or throat, or difficulty breathing. Also, call your doctor for any signs of neurological issues, like sudden weakness or tingling.

Based on current data, the protection from the RSV vaccine lasts for at least one full season and possibly into a second. As of now, the CDC recommends it for seniors based on shared clinical decision-making, but it is not typically an annual vaccine like the flu shot.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice. Always consult a qualified healthcare provider regarding personal health decisions.