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What is the ALZ Discovery Grant Program? Unlocking Research Potential

2 min read

With hundreds of millions of dollars invested in research, the Alzheimer's Association is a global leader in the fight against dementia. Their ALZ Discovery Grant Program specifically targets the critical gap between basic scientific discovery and the translation into effective treatments by leveraging pre-existing research resources.

Quick Summary

The ALZ Discovery Grant Program, offered by the Alzheimer's Association, funds projects that utilize existing animal models and extensive datasets, like those from the MODEL-AD AD Knowledge Portal, to propel promising basic science discoveries toward clinical application for Alzheimer's disease.

Key Points

  • Leverages Existing Resources: The program funds projects using established datasets and animal models.

  • Accelerates Translational Research: It bridges the gap between basic discoveries and new treatments.

  • Supports Multidisciplinary Collaboration: Preference is given to collaborative projects.

  • Includes Global Eligibility: The grant is open to diverse researchers and institutions globally, including for-profits.

  • Features Tiered Funding: Maximum funding is $250,000, with a $100,000 limit for purely computational projects.

  • Mandates Data Sharing: Awardees must share data and results within 12 months via public portals.

In This Article

Understanding the Program's Vision

Since awarding its first grants in 1982, the Alzheimer's Association has become the largest private, nonprofit funder of Alzheimer's research worldwide, fueling thousands of projects across the globe. The ALZ Discovery Grant Program was established to address the challenge of translating laboratory discoveries into clinical practices. The program funds research capitalizing on existing resources like datasets and animal models.

Core Objectives of the ALZ Discovery Program

Key objectives include leveraging existing resources, promoting multidisciplinary collaboration, and accelerating translational research. This aims to fast-track progress.

Eligibility and Application Requirements

The Alzheimer's Association has specific eligibility criteria. The process starts with a Letter of Intent (LOI).

Who Can Apply?

The grant is open to U.S. and international researchers at various institutions, including for-profit organizations. Postdoctoral fellows and faculty at different levels are welcome, with encouragement for scientists from underrepresented groups.

Who is Not Eligible to be a Primary Applicant?

State and federal government-appropriated laboratories cannot be the primary applicant institution.

Funding Details and Allowable Costs

Funding amounts depend on project scope and resources used. The maximum is $250,000, capped at $100,000 for projects using only downloadable data. Project duration is up to 3 years for those with live animals and up to 2 years otherwise. Indirect costs are limited to 10%. Allowable costs cover research support like salaries, animal costs, equipment, and travel for required meetings.

The Commitment to Open Science and Data Sharing

The ALZ Discovery Grant emphasizes open science, requiring data sharing to promote transparency and prevent redundant work. Data should typically be shared within 12 months through platforms like the AD Knowledge Portal.

ALZ Discovery vs. Other Alzheimer's Grants

The ALZ Discovery Grant focuses on using existing resources, unlike programs supporting early-career investigators generating initial data. For more detailed information on available funding, visit the {Link: Alzheimer's Association's grants page https://www.alz.org/research/for_researchers/grants}.

Feature ALZ Discovery Grant Program AARG Program
Primary Focus Utilizing existing datasets and animal models for translational research Supporting early-career investigators to generate pilot data
Funding Limit Up to $250,000 Up to $200,000
Duration Up to 3 years (animal) or 2 years (computational) Up to 3 years
Eligibility Postdocs, faculty, and for-profits from diverse global organizations Early-career faculty (<15 years post-PhD/MD)

Conclusion: Accelerating Discovery Together

The ALZ Discovery Grant Program accelerates research by prioritizing efficiency and collaboration, aiming to expedite the journey from lab discovery to patient therapies. By encouraging researchers to build upon shared resources, it fosters innovation to find new treatments and a cure for Alzheimer's and related dementias.

Frequently Asked Questions

Its primary objective is to fund research using existing resources to accelerate the translation of basic science into new treatments for Alzheimer's and related dementias.

Researchers at various institutions, including postdocs and faculty globally, can apply.

Yes, for-profit organizations are eligible.

The maximum award is $250,000, capped at $100,000 for purely computational projects. The duration can be up to three years.

Yes, data and findings must be shared through public databases, typically within 12 months.

This grant focuses on using existing resources, unlike those funding early-stage pilot data.

Yes, collaborative projects are given preference.

Applicants are expected to utilize resources such as datasets from the MODEL-AD AD Knowledge Portal or animal models from The Jackson Laboratory, among others.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice. Always consult a qualified healthcare provider regarding personal health decisions.