Updated Vaccines for Seniors in 2025
Staying up-to-date with vaccinations is a critical component of preventative healthcare for seniors. In 2025, several key vaccines have new recommendations or updated formulations aimed at providing better protection against circulating viruses. The most notable updates concern Respiratory Syncytial Virus (RSV) and COVID-19, with special formulations also recommended for annual influenza shots.
The Latest on Respiratory Syncytial Virus (RSV) Vaccines
New RSV vaccines have been licensed and recommended by the CDC for adults aged 60 and older. Three approved vaccines — Arexvy (GSK), Abrysvo (Pfizer), and mResvia (Moderna) — are licensed for older adults. A single administration is recommended for eligible adults and offers protection for at least one to two seasons. Vaccination in late summer or early fall (August-October) is recommended for best protection before RSV season. All adults 75 and older are recommended to get a single administration. Adults 50–74 at increased risk of severe RSV due to underlying health conditions should also get vaccinated.
The 2025-2026 COVID-19 Vaccine Update
COVID-19 vaccine formulations are updated annually. The 2025-2026 formulations target the LP.8.1 Omicron strain. Updated COVID-19 vaccines from Pfizer, Moderna, and Novavax are approved for adults aged 65 and older. The CDC recommended in October 2024 that adults 65 and older receive a second 2024-2025 COVID-19 vaccine six months after their last administration. Those who are moderately or severely immunocompromised may need additional doses based on clinical guidance.
Influenza (Flu) Vaccines for 2025-2026
Annual flu shots are important for seniors, with specific high-dose or adjuvanted versions recommended for a stronger immune response. High-dose (e.g., Fluzone High-Dose) and adjuvanted (e.g., Fluad) flu vaccines are preferred for those 65 and older as they are more effective than standard-dose options. The flu vaccine is updated annually to target the predicted common strains. Fall, ideally by the end of October, is the best time for older adults to get their annual flu vaccine.
Comparison of Recommended Vaccines for Seniors
Here is a comparison of key vaccines recommended for seniors in 2025.
| Vaccine Type | Recommended for Seniors (65+) | Schedule | Key Benefit for Seniors | Notes |
|---|---|---|---|---|
| RSV (Arexvy, Abrysvo, mResvia) | Yes | Single administration | Prevents severe RSV infection and hospitalization | First licensed for older adults starting in 2023. |
| COVID-19 (Updated 2025-26) | Yes | Two administrations for 65+ (6 months apart) | Updated formula targets current virus strains | New FDA guidance and ACIP recommendations apply. |
| Influenza (High-Dose/Adjuvanted) | Yes (Preferred) | Annually | Stronger immune response than standard flu shots | Specific options like Fluzone High-Dose, Fluad, and Flublok. |
| Shingles (Shingrix) | Yes (Recommended for 50+) | Two administrations (2-6 months apart) | Prevents shingles and long-term nerve pain | Recommended even if previously vaccinated with older Zostavax. |
| Pneumococcal | Yes (Recommended) | Varies by age and history | Prevents pneumonia and other serious infections | Two types of vaccines may be used. |
Important Consideration: Coadministration of Vaccines
Receiving multiple vaccines at the same visit is generally safe and often recommended to improve vaccination rates. Temporary side effects like pain or fever might increase. The RSV vaccine can be given with the flu or COVID-19 shot, though data on combined immune response is still being gathered. A healthcare provider can advise on the best timing.
Finding and Accessing the Vaccines
These vaccines are widely available at healthcare providers, pharmacies (like Walgreens and Safeway), and clinics. Medicare Part D and most private insurance cover ACIP-recommended vaccines like RSV and shingles with no out-of-pocket costs. Medicare Part B covers annual flu and COVID-19 shots. Confirm coverage with your provider.
Conclusion
In 2025, seniors have access to new and updated vaccines offering strong protection against serious respiratory illnesses. This includes multiple RSV vaccines, an updated COVID-19 shot, and special high-dose flu shots. Seniors should consult their healthcare provider to determine the best personalized vaccination plan. Staying informed and vaccinated helps older adults protect their health throughout the year.
Frequently Asked Questions (FAQs)
What are the main new injections for seniors in 2025?
The main new injections for seniors include the updated 2025-2026 COVID-19 vaccine targeting current circulating strains and the relatively new single-administration RSV vaccine, with several approved options available.
Is the RSV vaccine an annual shot like the flu shot?
A single administration is recommended for eligible adults, with protection lasting for at least one to two seasons. {Link: Washington State Department of Health doh.wa.gov}
How many COVID-19 shots do seniors need in 2025?
The CDC has recommended that all adults aged 65 and older receive two administrations of the updated 2024-2025 COVID-19 vaccine, with the doses separated by six months.
What are the side effects of the new RSV vaccine?
Common side effects can include fatigue, fever, headache, and pain or swelling at the injection site.
Can a senior get the flu shot, COVID shot, and RSV shot all at once?
Yes, coadministration of these vaccines is generally safe and often recommended. However, getting multiple shots at once may increase temporary side effects, such as fever or headache. Discussing the best approach with a healthcare provider is recommended.
Does Medicare cover these new senior injections?
Yes, Medicare typically covers these vaccines. Medicare Part B covers the annual flu and COVID-19 vaccines, while Medicare Part D covers other commercially available vaccines, like the RSV and shingles shots, with no out-of-pocket costs for ACIP-recommended vaccines.
What is Shingrix and is it new for seniors?
Shingrix is the recommended shingles vaccine for adults aged 50 and older. It is a newer and more effective vaccine than the older Zostavax, which was discontinued. Shingrix is a two-administration series recommended even for those who have previously had shingles or received Zostavax.
Do I need a doctor's prescription to get these vaccines?
You typically do not need a prescription for recommended vaccines like the flu, COVID-19, or shingles shots, which are widely available at pharmacies. However, it is always best to consult with your healthcare provider to confirm eligibility and discuss any potential risk factors.
