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What is the science behind ageLOC?

4 min read

According to Nu Skin, ageLOC is a proprietary technology developed in collaboration with scientific experts and a genomics company. This article answers the question, What is the science behind ageLOC?, by exploring its core principles of gene expression, ingredient selection, and how it purports to influence the aging process at a cellular level.

Quick Summary

The science behind ageLOC focuses on gene expression, utilizing research to identify what Nu Skin calls Youth Gene Clusters (YGCs) that influence the aging process. It then incorporates specific ingredients intended to 'reset' these YGCs back to more youthful patterns of activity, targeting the ultimate sources of aging, not just the symptoms.

Key Points

  • Gene Expression Focus: ageLOC science is built on the study of gene expression, the process dictating how genes function and how their activity changes over time.

  • Targeting Youth Gene Clusters (YGCs): The technology identifies specific functional gene groups, or YGCs, that are tied to aging, aiming to 'reset' their activity to more youthful patterns.

  • Strategic Partnerships: The research is supported by a collaboration with LifeGen Technologies, a genomics company, providing access to extensive genetic research.

  • Proprietary Ingredient Blends: Products contain unique blends of ingredients selected for their ability to modulate gene expression and target the sources of aging.

  • Broad Spectrum Application: ageLOC is used in both topical skincare systems (e.g., Boost, LumiSpa) and nutritional supplements (e.g., Youth) to provide both internal and external anti-aging benefits.

  • Beyond Superficial Treatment: The core principle is to address the underlying genetic causes of aging rather than just treating the visible symptoms on the surface.

In This Article

Understanding the Concept of Gene Expression

At the heart of the ageLOC technology is the concept of gene expression. This is the process by which instructions in our DNA are converted into a functional product, like a protein. As we age, the activity and expression patterns of our genes change. Some genes become more active, while others become less so. Nu Skin's research, in collaboration with genomics experts at LifeGen Technologies, identifies specific functional groups of genes, known as Youth Gene Clusters (YGCs), that are responsible for aspects of aging. By studying these gene patterns, they claim to understand how to influence them.

The Role of Youth Gene Clusters (YGCs)

Nu Skin's approach is centered on identifying and targeting these YGCs, which they consider the ultimate sources of aging. Instead of simply treating the visible signs of aging like wrinkles, ageLOC aims to influence these underlying genetic factors. The goal is to develop ingredient blends that can modulate the activity of these YGCs, helping them to behave in a more youthful manner. This is a key differentiator from traditional anti-aging products that typically focus on surface-level improvements.

The Partnership with LifeGen Technologies

A crucial component of the ageLOC narrative is the exclusive partnership with LifeGen Technologies. This U.S.-based genomics company has over 30 years of experience researching the genetic basis of aging. The collaboration gives Nu Skin exclusive access to LifeGen's extensive genetic research database, which has been instrumental in identifying the specific YGCs targeted by ageLOC products. This partnership is positioned to add significant credibility to Nu Skin's scientific claims and fuels the ongoing development of new products based on gene expression research.

How ageLOC's Ingredients and Delivery Work

The ageLOC technology is incorporated into both topical skincare products and nutritional supplements. The products contain proprietary blends of ingredients, which are carefully selected based on their ability to modulate gene expression.

Topical ageLOC Products

  • ageLOC Boost: This skincare system uses a patent-pending microcurrent technology combined with a conductive serum. The variable pulse microcurrent is said to optimize and activate the skin, helping the serum's potent ingredients target the visible signs of aging. The serum includes a blend of brightening and plumping ingredients alongside the ageLOC blend.
  • ageLOC LumiSpa: This device uses proprietary Micropulse Oscillation technology with a silicone treatment head to cleanse and promote skin renewal. It works by moving at a precise frequency to gently cleanse while delivering its own ageLOC-infused cleanser.
  • ageLOC Transformation Skincare: This set of products, including the Future Serum, contains a potent blend of ingredients that target the sources of aging and stimulate youthful cell turnover.

ageLOC Nutritional Supplements

  • ageLOC Youth: This supplement contains a blend of ingredients selected for their health benefits and ability to positively impact gene expression related to healthy aging. It is formulated to support multiple body functions, including cellular, brain, heart, metabolic, and skin health.
  • Key ingredients: The ingredients in these supplements are often derived from foods not commonly found in the average diet and are chosen for their unique properties. Nu Skin uses its proprietary 6S Quality Process to ensure the quality, efficacy, and safety of its supplements.

Comparing ageLOC to Other Anti-Aging Approaches

Feature ageLOC Technology Traditional Anti-Aging Cellular Rejuvenation (Research)
Target Gene expression, Youth Gene Clusters (YGCs) Visible signs of aging (wrinkles, spots) Epigenetic marks, partial reprogramming
Mechanism Resetting gene activity to more youthful patterns Surface-level treatment, stimulating collagen Resetting biological clock at a cellular level
Key Focus Targeting the “sources” of aging Treating the “symptoms” of aging Reversing cellular decline
Application Topical and nutritional products Topical creams, serums, and procedures Gene therapies, experimental interventions
Scientific Basis Proprietary research, gene expression studies Known anti-aging compounds (e.g., Retinol) Cutting-edge genomics, cell biology

The Role of Epigenetics in AgeLOC

Epigenetics refers to changes in gene expression that do not involve altering the underlying DNA sequence. ageLOC's focus on modulating Youth Gene Clusters is a form of epigenetic intervention. By using targeted ingredient blends, the technology aims to influence the 'software' that tells the body's DNA how to function. This contrasts with the idea that aging is solely caused by DNA mutations, which are more like permanent errors. ageLOC operates on the principle that many age-related changes are predictable and, to some extent, reversible by influencing these epigenetic patterns. This perspective is a central pillar of the company's scientific rationale.

The Future of ageLOC and Anti-Aging Research

The ongoing collaboration with LifeGen Technologies and other scientific partners suggests a commitment to continuous research and development. This includes exploring new insights into how skin ages, as well as broader anti-aging strategies that extend beyond visible effects. The company is positioned to continue leveraging its access to genetic research to develop innovative products. As the field of genetics and anti-aging research evolves, the principles behind ageLOC technology will likely adapt, targeting new gene expressions and biological markers discovered through ongoing studies.

Outbound Link

For more information on the broader field of genetic and epigenetic aging research, explore the Wyss Institute for Biologically Inspired Engineering at Harvard University where researchers are studying how to reverse aspects of aging by restoring epigenetic information.

Conclusion: The Holistic View of ageLOC Science

Ultimately, the science behind ageLOC is a multi-faceted approach centered on proprietary research into gene expression and what Nu Skin calls Youth Gene Clusters. By leveraging decades of genetic research from partners like LifeGen Technologies, the company has developed a range of products, both topical and ingestible, that are intended to modulate gene activity. This science moves beyond superficial anti-aging tactics to address what Nu Skin positions as the underlying causes of visible and internal aging. The emphasis on proprietary science and specific ingredient blends is the cornerstone of its anti-aging philosophy, targeting the body's natural aging mechanisms to promote a more youthful pattern of activity.

Frequently Asked Questions

The primary scientific principle behind ageLOC is the concept of gene expression. The technology identifies specific groups of genes, called Youth Gene Clusters (YGCs), that influence the aging process. By using proprietary ingredient blends, the products aim to modulate the expression of these genes, helping them function in a more youthful manner.

Youth Gene Clusters (YGCs) are functional groups of genes that Nu Skin identifies as key drivers of aging. These gene clusters are considered the ultimate sources of aging, and ageLOC technology is designed to target and reset their activity patterns to a more youthful state.

Nu Skin collaborates with leading scientists and has an exclusive partnership with LifeGen Technologies, a US-based genomics company with over 30 years of experience researching the genetic basis of aging. This partnership provides the company with exclusive access to extensive genetic data and research.

No, ageLOC technology is incorporated into a range of products, including both topical skincare treatments like the ageLOC Boost and LumiSpa systems, and nutritional supplements such as ageLOC Youth. This broad approach aims to address aging from both internal and external perspectives.

While traditional anti-aging products often focus on treating the visible signs of aging, ageLOC purports to target the deeper, genetic sources of aging. Instead of just addressing wrinkles or fine lines on the surface, the technology is designed to influence the underlying gene expression patterns that cause those signs to appear.

ageLOC's focus on modulating gene expression is an example of epigenetic intervention. Epigenetics involves changes to gene activity without altering the DNA sequence itself. ageLOC's ingredient blends are intended to act on these epigenetic patterns, essentially 'updating' the cellular software to promote more youthful function.

The scientific foundation of ageLOC is based on proprietary research conducted in collaboration with its partners. Some claims, such as those related to the ageLOC Boost system, cite independent clinical testing. However, the broader claims about resetting gene clusters are based on the company's own research, so a critical evaluation of the specific evidence is important.

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice. Always consult a qualified healthcare provider regarding personal health decisions.