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A Comprehensive Guide: What Vaccines Should Older Adults Get?

4 min read

According to the National Council on Aging, people 65 years and older bear the greatest burden of severe flu disease, accounting for 70-85% of seasonal flu-related deaths. Knowing exactly what vaccines should older adults get is a critical step in maintaining health and protecting against serious, preventable illnesses.

Quick Summary

Protecting against serious illness in later years involves specific immunizations like seasonal flu, shingles, pneumococcal, RSV, and Tdap, with recommendations that can change based on age and health status according to CDC guidelines.

Key Points

  • Annual Flu Shot: Older adults should receive a flu shot every year, with high-dose or adjuvanted options preferred for those 65+ for stronger protection.

  • Shingles (Shingrix): All healthy adults 50 and older need a two-dose series of Shingrix to prevent shingles and postherpetic neuralgia.

  • Pneumococcal Protection: The CDC lowered the age for routine pneumococcal vaccination to 50+ in 2025; ask your doctor if you're due.

  • RSV Vaccine: Adults 75+ and high-risk individuals 50-74 are recommended to get a single dose of the RSV vaccine.

  • Tdap Booster: Ensure you have had one dose of Tdap as an adult, followed by a Td or Tdap booster every 10 years for protection against tetanus and diphtheria.

  • Consult a Professional: Always talk to a healthcare provider for personalized advice on your immunization needs based on your health history.

In This Article

Why Immunizations Are Vital for Seniors

As we age, our immune systems naturally weaken, a process known as immunosenescence. This makes older adults more susceptible to infections and increases the risk of severe complications from diseases that might be mild in younger people. Vaccinations bolster the body's defenses, providing a critical shield against these threats. Beyond personal protection, staying up-to-date on vaccines also protects family, friends, and community members, including those who are immunocompromised.

Core Vaccines Recommended for Older Adults

Seasonal Influenza (Flu) Vaccine

Getting an annual flu shot is one of the most effective ways to prevent influenza and its severe outcomes. For adults aged 65 and older, the CDC preferentially recommends a higher-dose or adjuvanted flu vaccine, as these are formulated to produce a stronger immune response. Even if a preferred vaccine isn't available, any age-appropriate flu vaccine is better than none. Immunity from flu shots decreases over time and flu strains change annually, making yearly vaccination essential.

Shingles Vaccine (Shingrix)

Shingles is caused by the same virus as chickenpox, which can reactivate later in life. It causes a painful, blistering rash and can lead to severe, long-term nerve pain known as postherpetic neuralgia. The Shingrix vaccine is highly effective at preventing both shingles and this complication.

  • Who needs it: Healthy adults aged 50 and older. Also for adults 19 and older who are immunocompromised.
  • Dosage: Two shots, typically administered 2 to 6 months apart.
  • Note: It is recommended even if you've had shingles in the past or previously received the older Zostavax vaccine.

Pneumococcal Vaccines

Pneumococcal disease can cause serious illnesses like pneumonia, meningitis, and bloodstream infections. Older adults are at increased risk for severe disease. In 2025, the CDC updated its guidance, lowering the age recommendation for pneumococcal vaccination.

  • Who needs it: All adults aged 50 and older who are PCV-naive.
  • Dosage: For those who haven't had a pneumococcal conjugate vaccine (PCV), one dose of a newer PCV (PCV20 or PCV21) is recommended. A specific sequence involving PCV15 followed by PPSV23 is also an option. Your doctor can determine the best course based on your history.

RSV (Respiratory Syncytial Virus) Vaccine

RSV is a common respiratory virus that can be dangerous for older adults, causing serious lung infections and potentially fatal outcomes. New vaccines are available to provide protection.

  • Who needs it: All adults aged 75 and older are recommended to receive a single dose. For adults 50-74, a single dose is recommended based on individual risk factors and shared clinical decision-making.
  • Dosage: A single dose, and it is not currently an annual vaccine.
  • Timing: The best time to get vaccinated is in late summer or early fall, before the RSV season begins.

Tdap and Td Vaccines

These vaccines protect against tetanus, diphtheria, and pertussis (whooping cough), which can all be severe, especially for older adults.

  • Who needs it: Every adult should receive a one-time dose of Tdap if they did not receive it as an adolescent or if they are in close contact with infants. After that, a booster of either Tdap or Td is recommended every 10 years.

Considering Additional Vaccinations and Latest Updates

COVID-19 Vaccine

Recent CDC guidance focuses on staying up-to-date with updated 2025 COVID-19 vaccine formulations, with a shift toward individual decision-making for those under 65 and an emphasis on risk-benefit for those 65+. Older adults and those with underlying health conditions are at highest risk and should prioritize this vaccine.

Hepatitis B

Vaccination may be recommended for adults aged 60 and older with specific risk factors, such as chronic liver disease or other health concerns. This is determined on a case-by-case basis with a healthcare provider.

Comparison of Key Senior Vaccines

Vaccine Recommended Age Doses Frequency Primary Protection
Flu All adults; high-dose/adjuvanted for 65+ 1 Annually Seasonal influenza
Shingrix 50+ (or 19+ if immunocompromised) 2 Once in a lifetime Shingles (herpes zoster)
Pneumococcal 50+ (PCV-naive) Varies (1-2) Varies Pneumonia, meningitis
RSV 75+ (or 50-74 if high-risk) 1 Not currently annual Respiratory syncytial virus
Tdap/Td All adults 1 (Tdap) Td booster every 10 years Tetanus, diphtheria, pertussis

How to Determine Your Vaccination Needs

Consulting with your doctor or pharmacist is the best way to develop a personalized immunization plan. They can review your medical history and vaccination records to determine what you've already had and what you might be due for. This is especially important for vaccines like the pneumococcal series, where the correct regimen depends on your prior vaccinations. Your healthcare provider can also help you understand coverage details under Medicare or private insurance plans. A useful resource to discuss with your provider is the official adult immunization schedule, available on the CDC website.

Conclusion

Staying current on immunizations is a simple yet powerful strategy for safeguarding your health during your senior years. With updated recommendations for diseases like pneumococcal and the availability of new vaccines for RSV, there are more tools than ever to help older adults remain active and healthy. Don't wait until illness strikes; be proactive about your health and discuss your vaccination plan with a healthcare professional today.

Frequently Asked Questions

Yes, many vaccines, such as the flu and pneumococcal shots, can be co-administered during the same visit. This is often recommended for convenience, but it's best to discuss the plan with your healthcare provider.

If your vaccination history is unknown, your healthcare provider can help you determine the appropriate immunizations based on current age-based recommendations. It's often safer to get revaccinated than to risk being unprotected.

Medicare covers many essential adult vaccines. Part B typically covers flu and pneumococcal shots, while Part D covers others like shingles and Tdap. There are generally no out-of-pocket costs for vaccines recommended by the Advisory Committee on Immunization Practices (ACIP).

Yes, the CDC recommends specific high-dose or adjuvanted flu vaccines for people 65 and older. While side effects may be slightly more common, they are generally mild, and the increased effectiveness outweighs the discomfort.

Yes, the CDC recommends the Shingrix vaccine even if you have had shingles in the past. This is because the vaccine provides highly effective, long-lasting protection against recurrence.

Common side effects are typically mild and short-lived, such as soreness at the injection site, fatigue, or a low-grade fever. Severe allergic reactions are rare. For specific vaccine side effects, consult with your doctor or pharmacist.

The CDC updated its recommendations in 2025 based on rising rates of invasive pneumococcal disease in adults between 50 and 64, making the vaccine a proactive measure to protect a larger, more vulnerable adult population.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice. Always consult a qualified healthcare provider regarding personal health decisions.