The process of bone maturation, where the skeleton develops and hardens, is a complex process influenced by a variety of factors. It is not tied to a single age but rather a developmental phase marked by the fusion of growth plates and the attainment of peak bone mass.
The Role of Growth Plates
Growth plates, or physes, are areas of new bone growth found at the ends of the long bones in children and adolescents. They are made of cartilage and are responsible for lengthening the bones. When an individual stops growing in height, it's because these growth plates have hardened into solid bone in a process known as epiphyseal fusion.
- Closure timing varies: Growth plates don't all close at the same time. Those in the hands and feet typically close first, while those in longer bones like the femur close later.
- Visible on X-rays: On an X-ray, an open growth plate appears as a dark line. Once fused, this line disappears.
- Injury vulnerability: During a child's growing years, the growth plates are weaker than the solid bone and are more susceptible to injury.
Differences Between Males and Females
Skeletal maturation differs between males and females due to hormonal influences during puberty. Generally, girls mature earlier.
Skeletal Maturity in Females
Growth plate closure for girls typically occurs between ages 13 and 15, usually a year or two after menstruation begins. Height growth typically stops by age 14 or 15. While linear growth ceases, bone density continues to increase, with about 95% of peak bone mass reached by age 20 and further gains possible until 30. The fastest period of height growth for girls is around 11 to 12 years old.
Skeletal Maturity in Males
For boys, growth plates usually close between ages 15 and 18. Height growth generally stops around ages 16 to 18. Similar to females, peak bone mass is reached later, typically in the late 20s to early 30s. The fastest period of growth for boys is around age 13 to 14.
Factors Influencing Skeletal Maturity
Beyond gender, skeletal maturation is influenced by genetics, hormones, nutrition, and physical activity. Hormones like estrogen are crucial for growth plate fusion. Proper nutrition, especially calcium and vitamin D, and weight-bearing exercise are vital for bone density. Medical conditions can also impact timing.
Assessing Skeletal Maturity
Assessing skeletal maturity often uses X-rays of the hand and wrist, as discussed on {Link: OrthoInfo orthoinfo.aaos.org}. Methods include the Greulich and Pyle Atlas and the Tanner-Whitehouse Method. Other methods like the Risser Sign and Sanders Maturity Scale use the pelvis and hand/wrist respectively and are often used in conditions like scoliosis.
Common Assessment Methods
| Assessment Method | Area Examined | Description | Key Indicator | Applicability |
|---|---|---|---|---|
| Greulich and Pyle Atlas | Left hand and wrist | Compares a patient's X-ray to a series of standardized X-rays of average children at different ages. | Overall bone age based on wrist and hand bones. | Traditional method, though based on older data from a specific population. |
| Tanner-Whitehouse Method (TW2/TW3) | Left hand and wrist | Assesses the maturity of individual bones, assigning a score to each based on detailed criteria. | Total maturity score is calculated for a more precise bone age estimate. | Considered more objective than the atlas method. |
| Risser Sign | Pelvis | Uses a pelvis X-ray to track the ossification of the iliac apophysis, which fuses to the pelvic bone. | A scale from 1 (early puberty) to 5 (skeletally mature). | Commonly used for managing adolescent idiopathic scoliosis. |
| Sanders Maturity Scale | Left hand and wrist | A newer, 8-level scale that assesses bone maturity with better reliability for certain conditions like scoliosis. | Scale of 1 to 8, with 8 being full maturity. | More reliable for assessing peak growth velocity than the Risser sign. |
Conclusion
Skeletal maturity, marked by growth plate closure, typically occurs in the mid-to-late teens. However, peak bone mass is reached later, in the late 20s or early 30s. This process is influenced by genetics, gender, hormones, nutrition, and activity. Medical assessment using X-rays provides a more accurate 'bone age' than chronological age alone. Promoting good nutrition and weight-bearing exercise in youth is vital for long-term bone health.