Understanding cholesterol across the lifespan
Cholesterol, a waxy, fat-like substance found in your blood, is necessary for building healthy cells. However, excessive levels of "bad" low-density lipoprotein (LDL) cholesterol can contribute to plaque buildup in arteries, leading to atherosclerosis and increasing the risk of heart attack and stroke. High cholesterol often presents no symptoms, and while many associate it with older adults, it can begin in childhood due to genetic or lifestyle factors.
High cholesterol in children and adolescents
Major health organizations recommend universal cholesterol screening for all children, with the first test between ages 9 and 11, and another between 17 and 21 years old. Children with specific risk factors should begin screening as early as age 2. Early detection allows for the implementation of lifestyle changes, such as diet and exercise, to manage cholesterol before levels become critical. Treating high LDL cholesterol early significantly reduces long-term cardiovascular risks.
High cholesterol in adults
For most healthy adults with low heart disease risk, cholesterol testing is recommended every four to six years starting at age 20. After 40, a healthcare provider may use a risk calculator to personalize the screening schedule. More frequent testing is necessary for adults with higher risk profiles, such as those with a family history of premature cardiovascular disease, who are overweight or obese, have diabetes or high blood pressure, or who smoke. Cholesterol screening frequency typically increases with age: men ages 45 to 65 and women ages 55 to 65 typically screen every 1 to 2 years, with annual screening often recommended for adults over 65.
Familial vs. acquired high cholesterol
Feature | Familial Hypercholesterolemia (FH) | Acquired High Cholesterol |
---|---|---|
Cause | Genetic disorder inherited from parents. | Caused by lifestyle factors like poor diet, lack of exercise, obesity. |
Onset | Often present from birth, leading to high cholesterol from a young age. | Develops over time due to lifestyle habits and aging. |
Severity | Exceptionally high LDL levels (often over 190 mg/dL), resistant to lifestyle changes alone. | LDL levels vary, generally more responsive to lifestyle changes. |
Treatment Approach | Requires early, aggressive intervention, often medication (statins), plus lifestyle changes. | Initially managed with lifestyle changes; medication added if needed. |
Family Implications | Requires screening of all first-degree relatives. | Other family members may have high cholesterol due to shared lifestyle or mild genetic predisposition. |
The risk of delaying treatment
High cholesterol is a "silent" condition with no symptoms. Prolonged exposure to high LDL cholesterol leads to cumulative damage. Delaying treatment significantly increases the risk of cardiovascular events later in life. Early intervention, especially for high LDL-C, is crucial to prevent plaque formation and stabilize existing plaque. Even modest elevations, particularly in younger adults (35-55), warrant attention. Consistent screening and monitoring are important.
Conclusion
Universal screenings for children between 9 and 11, and again between 17 and 21, are recommended and should continue throughout adulthood. Risk factors may necessitate earlier and more frequent testing. Because high cholesterol typically has no symptoms, early detection through regular blood tests is essential. By adhering to recommended screening schedules and addressing risk factors, individuals can substantially reduce their risk of heart disease and stroke. Consult your healthcare provider to understand your personal risk and determine the most suitable screening plan for you.