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Do nerves get less sensitive with age? The neuroscience behind aging and sensation

6 min read

According to the National Institutes of Health, sensory systems often show a documented decrease in sensitivity as we age, including touch, taste, smell, and hearing. So, to answer the question, do nerves get less sensitive with age? The short answer is yes, nerves do become less sensitive due to a number of physiological changes.

Quick Summary

Nerve sensitivity decreases with age due to slower nerve communication, reduced number of nerve endings, and changes in the brain's processing of nerve signals. This leads to reduced senses of touch, vibration, and pain perception, impacting reaction time and balance. Healthy aging involves understanding these natural changes to mitigate associated risks.

Key Points

  • Sensation Declines with Age: Nerve sensitivity decreases naturally over time due to reduced nerve cell numbers, damaged myelin, and impaired blood flow, which impacts all five senses.

  • Impacts on Safety: Reduced sensitivity to pain, pressure, and touch increases the risk of falls and delayed injury detection, making safety precautions crucial.

  • Brain Processing Slows: Alongside peripheral changes, the brain's ability to process nerve signals and command reflexes also slows, affecting reaction time.

  • Sensory-Specific Changes: Common age-related sensory declines include high-frequency hearing loss, diminished taste and smell, and reduced peripheral vision.

  • Managing the Decline: Lifestyle factors like regular exercise and managing chronic conditions can help mitigate some age-related nerve changes and support overall nervous system health.

  • Adaptation is Key: Adapting to sensory changes, such as modifying home environments for safety and relying on compensatory cues, helps maintain independence and well-being.

In This Article

The Science of Aging Nerves

As we age, the nervous system, which includes the brain, spinal cord, and a vast network of nerves, undergoes a number of natural changes. These changes affect not only how we move and think but also how we experience the world through our senses. The reduction in nerve sensitivity is a complex process driven by several factors, including structural and functional alterations within the nervous system itself.

At a fundamental level, nerve cells, or neurons, begin to break down over time. This can lead to a decrease in the number of nerve cells and a reduction in the efficiency of signal transmission. Additionally, the protective myelin sheath surrounding nerve fibers can deteriorate, which further slows down nerve conduction velocity. Think of the myelin sheath as the insulation on an electrical wire—if it frays, the signal gets weaker and travels slower. This degradation is a core reason why reflexes and reaction times can decrease as we get older.

Factors Contributing to Reduced Nerve Sensitivity

Physiological Changes

  • Decreased Blood Flow: Reduced blood flow to nerve endings, the spinal cord, and the brain is a significant factor. Nerves, like all tissues, require a steady supply of oxygen and nutrients to function correctly. When blood flow is compromised, nerve function declines.
  • Loss of Sensory Receptors: Specialized sensory receptors in the skin, tongue, nose, and other parts of the body can decrease in number or function. For example, the number of taste buds declines after age 60, and nerve endings in the nose decrease, affecting both taste and smell.
  • Axon and Myelin Breakdown: The axons, which are the long, slender projections of nerve cells that conduct electrical impulses, can be lost or damaged. Coupled with the breakdown of myelin, this leads to a less efficient neural network overall.

Cellular and Metabolic Factors

  • Waste Product Buildup: A fatty brown pigment called lipofuscin can accumulate in nerve tissue, and other waste products can collect in the brain tissue. This can lead to the formation of plaques and tangles that further disrupt nerve communication.
  • Metabolic Issues: Research has suggested that low-level inflammation and impairments in glucose metabolism may accelerate the age-related decline of nerve function.
  • Neurotransmitter Changes: The efficiency of neurotransmitter function, which is critical for cell signaling, may decrease with age. This can affect mood, cognition, and sensory processing.

Common Sensory Changes Associated with Aging

The impact of reduced nerve sensitivity is felt across all five senses, but some are more affected than others.

Touch and Pain Perception

  • Vibratory Sensation: A reduced ability to perceive vibration is common, particularly in the lower extremities. This can impact balance and increase the risk of falls.
  • Pressure and Touch: Sensitivity to touch and pressure may also diminish. This increases the risk of injuries, such as pressure ulcers, as an older person may not feel discomfort or pressure in a localized area.
  • Pain Threshold: Many people over the age of 50 may experience a reduced sensitivity to pain. While this might seem beneficial, it can mask serious injuries and lead to delayed medical attention. However, paradoxically, chronic pain can become more prevalent and intense with age due to complex changes in the pain pathways.

Other Sensory Systems

  • Vision: Age-related vision changes include a decrease in visual acuity, peripheral vision, and adjustment to darkness. This is often linked to a drop-out of photoreceptors and retinal ganglion cells.
  • Hearing: High-frequency hearing loss, known as presbycusis, is very common. It can be caused by damage to cochlear hair cells or other changes in the auditory system.
  • Taste and Smell: The number of taste buds and olfactory nerve endings decreases, leading to a diminished sense of taste and smell. This can reduce appetite and enjoyment of food, and also pose a safety risk if one cannot detect gas leaks or spoiled food.

How to Adapt to Age-Related Sensory Changes

While some sensory decline is inevitable, there are strategies to help manage and mitigate its impact on daily life.

  • Regular Exercise: Staying physically active can improve blood flow throughout the body, including to nerve endings, potentially slowing down some age-related changes.
  • Manage Chronic Conditions: Conditions like diabetes and high blood pressure can accelerate nerve damage. Proper management of these conditions is crucial for protecting nerve health.
  • Ensure Home Safety: With reduced touch and vibratory sensation, a person's risk of falls increases. Fall prevention strategies, such as installing grab bars, improving lighting, and removing trip hazards, are essential.
  • Compensate with Other Senses: Pay more attention to visual and auditory cues to compensate for reduced touch sensitivity. For example, relying on visual inspection for injuries rather than waiting for a pain signal.
  • Utilize Safety Devices: Install gas leak detectors with audible alarms and fire alarms in the home to compensate for a reduced sense of smell. Set water heater temperatures to a safe level (120°F / 49°C) to prevent burns from reduced heat sensitivity.

Comparison of Nerve Function: Young vs. Aged Adults

Characteristic Young Adult Aged Adult
Nerve Conduction Velocity Fast and efficient Slower, due to myelin breakdown
Number of Nerve Endings Plentiful Reduced, affecting sensation
Sensation Sharp and responsive Reduced, particularly touch, vibration, and pain
Reflexes Quick and automatic Slower and less responsive
Processing Speed Faster, especially for new information Slower, may require more cognitive effort
Risk of Falls Lower Higher, due to decreased sensation and balance

Conclusion

The fact that nerves do get less sensitive with age is a well-established scientific reality. These changes, resulting from a combination of cellular degradation, reduced blood flow, and other physiological factors, can impact all the senses and affect daily activities. While we cannot stop the aging process, understanding these shifts allows for proactive measures to maintain a high quality of life. By focusing on overall health, managing existing conditions, and creating a safe environment, older adults can navigate these sensory changes and live more securely and independently. For further reading on the neuroscience of aging, consider resources like the National Institute on Aging's page on the aging brain and nervous system: National Institute on Aging: The Changing Brain.

Summary of Key Findings

  • Nerve sensitivity decreases with age due to cellular breakdown, reduced blood flow, and myelin deterioration, causing signals to slow down.
  • Multiple senses are affected, with a notable decline in touch, taste, smell, and the perception of pain, vibration, and pressure.
  • Impaired sensation can increase risks, such as a higher risk of falls due to poor balance and a greater chance of accidental injury due to reduced pain perception.
  • Home safety modifications are crucial to mitigate risks posed by reduced sensation, such as lower water temperatures and reliable smoke detectors.
  • Proactive health management is key, including exercise and managing conditions like diabetes, to support overall nerve health and function.

Actionable Insights

  • Stay active to promote circulation and support overall nervous system health.
  • Manage underlying health issues like diabetes and high blood pressure, which can accelerate nerve damage.
  • Enhance safety measures at home to compensate for reduced sensation and prevent falls.
  • Monitor sensory changes and report significant issues to a healthcare provider for proper diagnosis and management.
  • Adjust daily habits to compensate for sensory decline, such as visually checking for injuries or using safety alarms.

A Final Word on Healthy Aging

Embracing healthy aging means acknowledging the body's natural changes and adapting accordingly. While less sensitive nerves may be a consequence of getting older, a proactive and informed approach can help individuals maintain their independence and well-being. By understanding the underlying biology and implementing practical strategies, it is possible to live a safe, fulfilling, and aware life at any age. While the senses may change, the ability to adapt and thrive remains. This knowledge empowers seniors and their caregivers to address potential risks effectively and focus on what truly matters: enjoying a healthy and active lifestyle.

Frequently Asked Questions

The primary reason is a combination of factors, including a decrease in the number of nerve endings, the breakdown of the myelin sheath that insulates nerves, and reduced blood flow to nerve tissues. These changes cause nerve signals to transmit more slowly and less effectively.

Yes, absolutely. Reduced sensation, particularly in the lower extremities, can impair a person's ability to feel pressure and vibration. This directly affects balance and spatial awareness, significantly increasing the risk of falls.

No, the impact varies. While senses like touch, taste, and smell often show a documented decline, the degree can differ between individuals. For example, sensitivity to vibration is a common early change, while some individuals might experience more pronounced changes in hearing or vision.

It is not uncommon for individuals over 50 to have a reduced sensitivity to pain. This is a result of age-related nerve changes. While it may sound beneficial, it can be dangerous as it can mask serious injuries that require medical attention.

While it is a natural part of aging, you can manage and potentially slow down the effects. Regular exercise to improve circulation, managing chronic diseases like diabetes, and maintaining a healthy diet can all support nerve health. Additionally, protecting your nerves from damage through safe practices is important.

You can adapt by modifying your home environment and using compensatory strategies. This includes ensuring adequate lighting, using safety alarms for gas or smoke detection, and regularly inspecting your body (especially feet) for injuries you might not feel. Compensation with other senses and careful attention to detail are key.

Normal age-related changes are gradual and widespread, affecting various sensory perceptions. Neuropathy, on the other hand, is a specific type of nerve damage that can cause pain, numbness, or weakness, often stemming from an underlying disease like diabetes. If you notice specific nerve-related symptoms, consult a doctor to rule out neuropathy.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice. Always consult a qualified healthcare provider regarding personal health decisions.