Why the Whites of Your Eyes Can Turn Yellow
Yellowing of the eyes, a condition medically known as scleral icterus or conjunctival icterus, is frequently associated with an increase in bilirubin levels in the bloodstream. Bilirubin is a yellowish pigment that is a byproduct of the normal breakdown of red blood cells. Typically, the liver processes this bilirubin and excretes it, but if the liver is not functioning correctly or if the bile ducts are blocked, bilirubin can accumulate and cause visible yellowing in the whites of the eyes and skin. Many of the conditions that lead to this are more prevalent in older adults.
Jaundice and Bilirubin Buildup
Jaundice is the most common reason for widespread yellowing of the sclera. It indicates that the liver, gallbladder, or pancreas is not functioning as it should. The risk factors for these issues tend to increase with age. Common causes include:
- Liver disease: Conditions like cirrhosis (scarring of the liver), hepatitis (liver inflammation), and non-alcoholic fatty liver disease can all disrupt the liver's ability to process bilirubin.
- Bile duct obstruction: Gallstones, inflammation of the pancreas (pancreatitis), or tumors can block the bile ducts, preventing bilirubin from being excreted.
- Hemolytic anemia: This blood disorder causes red blood cells to break down faster than the liver can process them, leading to a bilirubin surplus.
- Certain medications: Long-term or excessive use of some drugs, including acetaminophen, antibiotics, and anabolic steroids, can potentially damage the liver and cause yellowing.
Ocular Conditions Mimicking Yellowing
It is important to distinguish between systemic yellowing caused by jaundice and more localized yellow growths on the eye's surface. With age, long-term exposure to ultraviolet (UV) light, wind, and dust can lead to specific, non-jaundice related changes.
- Pingueculae: These are yellowish, raised growths on the conjunctiva (the transparent tissue covering the white of the eye). They are most common in the inner or outer corners of the eye, where sun exposure is highest.
- Pterygia: A pterygium is a similar, but more advanced, growth that can extend from the conjunctiva over the cornea. While it can appear yellowish, it is distinct from jaundice.
The Yellowing Lens (Not the Sclera)
Another change that can cause a yellow tint, but to your vision itself rather than the white of your eye, is the natural aging of the eye's lens. Over time, the lens can become yellowish or brownish, which can filter out blue light and change how colors are perceived. This is a progressive change associated with cataracts, which are very common in older adults.
Jaundice vs. Ocular Discoloration: A Comparison
To help differentiate between potential causes, consider this comparison:
| Characteristic | Jaundice (Bilirubin Buildup) | Ocular Growths (Pingueculae/Pterygia) |
|---|---|---|
| Appearance | Widespread yellowing of the entire sclera. Can also affect skin. | Localized, yellowish, raised growths, often in the inner/outer corners. |
| Associated Symptoms | Fatigue, itchy skin, dark urine, pale stools, abdominal pain. | Can cause irritation, redness, or a feeling of a foreign body in the eye. |
| Progression | Can develop relatively quickly and indicates a systemic issue. | Develops slowly over time from chronic environmental exposure. |
| Cause | Primarily related to liver, gallbladder, or blood disorders. | Primarily related to long-term UV radiation, wind, and dust exposure. |
When to See a Doctor About Yellow Eyes
Given that yellowing of the eyes can be a sign of a serious underlying health condition, it is crucial to consult a healthcare provider promptly. While some causes like pingueculae may be benign, others can indicate a life-threatening illness. You should seek immediate medical care if yellowing is accompanied by any of the following symptoms:
- Changes in mental status, confusion, or severe weakness
- Dark urine or pale, clay-colored stools
- Unexplained weight loss or loss of appetite
- Abdominal pain or swelling
- Fever or fatigue
Do not attempt to self-diagnose based on eye appearance alone. A doctor can perform blood tests and other diagnostic procedures to determine the exact cause.
Protecting Your Eyes as You Age
While not all age-related issues are preventable, you can take proactive steps to promote overall eye and liver health throughout your life:
- Wear UV-blocking sunglasses: Protecting your eyes from the sun's UV rays is the best defense against growths like pingueculae and pterygia.
- Maintain a healthy diet: A diet rich in antioxidants, vitamins, and omega-3 fatty acids supports liver function and overall eye health. Focus on leafy greens, citrus fruits, nuts, and fish.
- Stay hydrated: Proper hydration is essential for your body's organs, including the liver, to function effectively.
- Limit alcohol intake: Excessive alcohol consumption can lead to liver damage over time, which can cause jaundice and yellowing of the eyes.
- Get regular eye exams: Comprehensive eye exams can help detect early signs of age-related issues, as well as systemic health problems that manifest in the eyes.
For more information on general eye health as you age, the National Institute on Aging offers valuable resources.
The Takeaway: Yellow Eyes Are a Warning Sign
Ultimately, the appearance of yellow eyes is not a benign sign of growing older. While localized yellow spots might be harmless growths, widespread yellowing (jaundice) indicates that your body's systems, particularly the liver, are under stress. For anyone, and especially for seniors, taking this symptom seriously and consulting a medical professional is a critical step toward identifying and treating a potentially serious underlying condition. Protecting your eyes from UV damage and maintaining a healthy lifestyle are excellent ways to support your eye and overall health long-term.