Bryan Johnson's Use of NAD+ Boosters
Yes, Bryan Johnson explicitly includes NAD+ precursors in his exhaustive daily supplement stack as part of his Project Blueprint to reverse biological aging. His protocol is based on extensive personal testing and data collection, which has shown that boosting NAD+ levels is a key part of his strategy for cellular health. The tech entrepreneur has publicly shared his self-experimentation with both Nicotinamide Mononucleotide (NMN) and Nicotinamide Riboside (NR), two of the most popular NAD+ boosting supplements.
The Role of NAD+ in Bryan Johnson's Protocol
Nicotinamide adenine dinucleotide (NAD+) is a vital coenzyme found in every cell of the body that is crucial for a multitude of biological processes, including:
- Energy Production: Converting food into cellular energy within the mitochondria.
- DNA Repair: Activating sirtuins, a family of proteins that regulate cellular health and repair damaged DNA.
- Cellular Signaling: Playing a key role in various cell functions.
Since NAD+ levels naturally decline with age, Johnson's protocol targets this process directly through supplementation. He views maintaining youthful NAD+ levels as a core component of his anti-aging efforts. His blood tests confirmed that after incorporating these precursors, his NAD+ levels aligned with those of a much younger individual.
Comparing Bryan Johnson's Use of NMN vs. NR
Johnson's data-driven approach led him to perform a direct, personal comparison of NMN and NR. He used each supplement for 90 days to determine their effects on his biomarkers, particularly his NAD+ levels.
Comparison: NMN vs. NR in Bryan Johnson's Protocol
| Feature | Nicotinamide Mononucleotide (NMN) | Nicotinamide Riboside (NR) |
|---|---|---|
| Johnson's Testing | Used for a 90-day period during his personal trial. | Also used for a 90-day period to compare against NMN. |
| Efficacy | His measurements indicated that NMN effectively raised his NAD+ levels. | His measurements showed that NR was also effective at elevating NAD+ levels. |
| Equivalency | Johnson's personal data concluded that both NMN and NR were equally effective at raising his cellular NAD+ levels. | His findings demonstrated that NR was comparable to NMN in its ability to boost NAD+. |
| Shift in Protocol | After finding similar efficacy, Johnson has reportedly used NMN as part of his ongoing regimen. | He initially used NR before switching to NMN, indicating his protocol is subject to updates based on personal data and scientific findings. |
The Evolving Nature of Project Blueprint
Johnson's use of NAD+ precursors is not a static element of his protocol. It's an example of how he constantly adjusts his routine based on the latest scientific findings and his own measured biological responses. For instance, he also takes other supplements and performs other therapies that support cellular function and energy production, working in synergy with NAD+ enhancement.
His approach also involves monitoring various other biomarkers to ensure overall system health, rather than focusing on just one aspect. He measures organ health, cognitive function, inflammation, and more to create a comprehensive picture of his biological age. The inclusion of NAD+ precursors is a targeted intervention within this larger, holistic strategy. As new research emerges, or as his own biological data changes, it is likely that his specific supplementation will continue to evolve.
Conclusion
Bryan Johnson undeniably uses NAD+ precursors as a central component of his Project Blueprint longevity regimen, incorporating both NMN and NR at various times. He has rigorously tested these compounds on himself and concluded that both effectively raise cellular NAD+ levels. This practice is part of his broader, data-driven strategy to counter the natural decline of NAD+ that occurs with age, supporting enhanced cellular energy and repair. His ongoing self-experimentation and adaptation underscore his commitment to maximizing his health span and providing a real-world case study in biohacking and longevity practices.
Note: While Johnson's results are compelling anecdotal evidence, it is always recommended to consult a healthcare professional before starting any new supplement regimen. For more information on Johnson's full protocol, visit his website at blueprint.bryanjohnson.com.
