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Does Restless Leg Syndrome Get Worse as You Age?

4 min read

Restless Leg Syndrome (RLS) affects a significant portion of the older adult population, with some studies suggesting prevalence increases with age.

This raises a critical question for many: Does restless leg syndrome get worse as you age?

Quick Summary

The severity of Restless Leg Syndrome does not inevitably worsen with age for every individual. While overall prevalence increases in older adults, the course of the condition is highly variable and depends on underlying health factors and treatment effectiveness.

Key Points

  • Not a Guarantee: The severity of RLS does not inevitably increase with age; progression is highly individual.

  • Health Factors Influence Severity: Worsening symptoms are often linked to new comorbidities like kidney disease, diabetes, or medication side effects.

  • Iron is Key: Iron deficiency, which can be more common in older adults, significantly impacts RLS symptoms.

  • Medication Check-Up: A comprehensive review of all medications is crucial, as some drugs can worsen RLS.

  • Effective Management Exists: Lifestyle adjustments, including exercise and sleep hygiene, along with targeted treatments, can successfully control symptoms in older adults.

  • Differentiate RLS Types: The distinction between primary (idiopathic) and secondary RLS is important, as secondary forms are often tied to specific, treatable causes.

In This Article

Understanding the Complexities of RLS and Aging

Restless Leg Syndrome, also known as Willis-Ekbom disease, is a neurological condition characterized by an irresistible urge to move the legs, usually accompanied by uncomfortable sensations. These symptoms typically occur in the evening or night and are triggered by rest, making it a major disruptor of sleep. While the condition can start at any age, its impact and manifestation can change over a person’s lifetime.

Factors Influencing RLS Severity with Age

It is a misconception that RLS automatically becomes more severe with age. The trajectory is not linear and is influenced by a number of factors that often become more prevalent in older adults. These factors include:

  • Iron Deficiency: Iron plays a crucial role in dopamine pathways in the brain. As people age, they may experience changes in nutritional intake or absorption, leading to iron deficiency, which can exacerbate RLS symptoms.
  • Medications: Many older adults are on multiple medications for various health conditions. Some drugs, such as certain antidepressants, antihistamines, and anti-nausea medications, are known to trigger or worsen RLS symptoms.
  • Other Medical Conditions: Conditions like kidney failure, peripheral neuropathy, and diabetes become more common with age. These comorbidities can often be a secondary cause of RLS, meaning treating the underlying condition can alleviate the symptoms.
  • Peripheral Neuropathy: Nerve damage in the legs can cause abnormal sensations similar to RLS and often co-occurs with it. The prevalence of peripheral neuropathy increases significantly with age.

The Impact of Medication and Comorbidities

It is critical for seniors and their healthcare providers to evaluate all medications being taken. A medication review can identify potential culprits for worsening RLS. Similarly, addressing underlying health issues is a cornerstone of managing RLS in older adults. Instead of an inevitable progression due to age alone, a worsening of symptoms often points to a new or changing health factor.

Differentiating Primary vs. Secondary RLS

  • Primary (Idiopathic) RLS: This form has no known cause and is often genetic. It tends to begin earlier in life and progress slowly, if at all.
  • Secondary RLS: This form is caused by another medical condition or external factor, such as those listed above. It can appear later in life and may resolve if the underlying cause is treated. The perceived worsening of RLS with age is often a manifestation of a new secondary cause rather than the primary RLS itself advancing.

Comparison of RLS Symptom Trajectories

Symptom Aspect Progression in Younger Onset RLS Progression in Older Onset RLS
Onset Often gradual, slow progression over decades Can be more sudden, often linked to a specific cause
Severity May stabilize for long periods, not guaranteed to worsen More variable, can be tied directly to health changes
Response to Treatment Often very responsive to standard treatments Response can be complicated by multiple medications
Underlying Cause Often genetic; less likely secondary Often linked to comorbidities, medication, or nutrient deficiency

Effective Management Strategies for Seniors

Managing RLS in older adults requires a holistic and tailored approach. Treatment is not one-size-fits-all and should involve a detailed discussion with a healthcare provider.

Lifestyle and Non-Pharmacological Interventions

  • Regular Exercise: Gentle, regular physical activity, especially walking or stretching, can be highly effective. Avoid intense workouts close to bedtime.
  • Warm Baths and Massages: Soothing muscles before sleep can provide temporary relief from symptoms.
  • Establishing Sleep Hygiene: Maintaining a consistent sleep schedule and creating a calm, dark, and cool sleeping environment is crucial.
  • Avoid Triggers: Limit or avoid caffeine, alcohol, and nicotine, especially in the evening.
  • Supplements: If iron deficiency is identified, supplements can be beneficial, but should only be taken under medical supervision.

Pharmacological Treatment

Medication may be necessary for severe cases. Your doctor may consider:

  1. Dopamine Agonists: These drugs, such as pramipexole and ropinirole, increase dopamine levels in the brain.
  2. Alpha-2-Delta Ligands: Drugs like gabapentin are often effective for pain and are used off-label for RLS.
  3. Benzodiazepines: These sedatives may help with sleep but are generally prescribed for short-term use due to dependency risk.

It is important to find the right balance, as some RLS medications can have side effects, and some may lose effectiveness over time, a phenomenon known as augmentation.

The Role of Comprehensive Assessment

For seniors experiencing a change in their RLS symptoms, a complete medical assessment is the most important step. This should include a review of all current medications, a check for nutrient deficiencies (like iron), and screening for other conditions that might be influencing the symptoms. It is often a change in health status, not just chronological age, that drives symptom progression. The National Institute of Neurological Disorders and Stroke provides excellent resources for patients and caregivers on understanding RLS and its management: NINDS Restless Legs Syndrome Fact Sheet.

Conclusion: Age is Just One Factor

While the answer to does restless leg syndrome get worse as you age? isn’t a simple “yes,” the likelihood of experiencing more severe symptoms or a more complex presentation increases. This is primarily due to the higher chance of having comorbidities or taking medications that impact RLS. The good news is that these factors are often manageable. By working closely with a healthcare provider, older adults can effectively identify the causes of any symptom changes and implement strategies to maintain a good quality of life despite their RLS.

Frequently Asked Questions

The increased prevalence of RLS in older adults is often associated with the rise in comorbidities like kidney disease, diabetes, and nerve damage, as well as the use of certain medications that can trigger or worsen symptoms.

Yes, many medications can affect RLS. Common culprits include certain antidepressants (SSRIs), antihistamines, and some cold and flu remedies. Always discuss your medications with your doctor if your RLS symptoms change.

Iron deficiency can be a significant factor. Iron is vital for the brain's dopamine pathways, and insufficient levels can exacerbate RLS symptoms. Blood tests are needed to confirm deficiency, and supplements should only be taken under a doctor's guidance.

Absolutely. Non-drug treatments are often the first line of defense. These include regular, gentle exercise, warm baths, leg massages, avoiding caffeine and alcohol in the evening, and maintaining good sleep hygiene.

Augmentation is a side effect of some RLS medications where symptoms begin earlier in the day and become more intense. While not tied specifically to aging, older adults on long-term RLS medication are susceptible and may need their treatment plan reevaluated.

Yes, intense exercise, particularly close to bedtime, can sometimes worsen RLS symptoms. Moderate, regular exercise is generally recommended, but individuals should find a routine that works for them without overexerting themselves.

While RLS can be a standalone (primary) condition, it can also be a symptom of other issues (secondary). For older adults, it can be linked to conditions like peripheral neuropathy, kidney disease, or nutrient deficiencies, which require medical attention.

Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice. Always consult a qualified healthcare provider regarding personal health decisions.