Understanding Hormone Therapy in Later Life
Historically, it was standard practice to stop hormone therapy (HT) after age 60 or 65, influenced by initial findings from the Women's Health Initiative (WHI) study concerning risks like certain cancers and cardiovascular issues. However, newer research and re-evaluations offer a more complex view. The current medical approach emphasizes tailoring HT decisions to a woman's health, symptom severity, and treatment duration, moving away from age as the primary factor.
The Evolving Medical Perspective on Long-Term HT
Recent analyses, including a study of over 10 million senior Medicare women, suggest that the benefits and risks of continuing HT after 65 are significantly influenced by hormone type, delivery method (like oral vs. transdermal), and dosage. Low-dose transdermal estrogen, for instance, may have a better risk profile than higher-dose oral options. The Menopause Society's 2022 stance supports that age alone shouldn't mandate stopping HT. Continuing for persistent, bothersome symptoms can be appropriate with proper counseling and risk assessment.
Benefits of Considering Continued HT
For some women over 70, continuing HT can significantly improve their quality of life, often by managing persistent hot flashes.
Benefits may include:
- Symptom Management: Relief from hot flashes and night sweats.
- Improved Quality of Life: Better sleep and overall daily function by reducing disruptive symptoms.
- Bone Health: Estrogen can help maintain bone density, reducing osteoporosis and fracture risk.
- Vaginal and Urogenital Health: Localized estrogen effectively treats vaginal dryness and related urinary issues.
Assessing Risks and Mitigating Factors
HT risks generally increase with age and duration, making a detailed medical evaluation essential.
Key risks include:
- Cardiovascular Risks: Older women may have higher risks of stroke and blood clots, particularly with oral HT. Transdermal methods might be safer alternatives.
- Breast Cancer Risk: Combined estrogen and progestin therapy is linked to increased breast cancer risk, varying by specific formulation.
- Other Health Conditions: Existing conditions like high blood pressure, cholesterol, or a history of blood clots or breast cancer must be considered.
Key Considerations: Oral vs. Transdermal HT
Hormone delivery method impacts risk. The table below compares oral and transdermal HT.
| Feature | Oral Hormone Therapy | Transdermal Hormone Therapy |
|---|---|---|
| Administration | Pills taken by mouth | Patches, gels, or sprays applied to the skin |
| Liver Metabolism | Processed through the liver; can affect clotting factors | Bypasses the liver; avoids some potential risks |
| Cardiovascular Risk | Possibly higher risk of blood clots and stroke | Possibly lower risk of blood clots compared to oral |
| Dosage Control | Systemic dose, impacts entire body | Can be more localized or systemic, depending on application |
| Convenience | Easy to remember daily pill | Requires consistent application and skin integrity |
Transdermal delivery is often preferred for older women due to potentially reduced cardiovascular risk, but the choice requires consulting a healthcare provider.
How to Discuss HT with Your Doctor
Discussing HT with a doctor is crucial. Be prepared to cover:
- Symptom Severity: Describe how symptoms affect your daily life.
- Medical History: Share your personal and family medical history.
- Risk Assessment: Understand your individual risks.
- Treatment Options: Discuss types and delivery methods of HT.
- Ongoing Monitoring: Plan for regular follow-ups.
This shared decision-making helps determine the best path for your health needs.
Conclusion: A Personal, Informed Decision
There's no single answer to should a 70 year old woman take hormones. Current guidance favors an individualized approach based on persistent symptoms, quality of life, and a careful risk-benefit analysis. For women with significant ongoing symptoms and a suitable health profile, continuing or starting HT under medical care can be a valid option. A key resource for more information is The Menopause Society.